| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isobutyraldehyde 10.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN013_HEPG2_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 4.82252 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.66677 |
| LCN2 | lipocalin 2 | 4.64604 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 4.57066 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 4.00755 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 3.59158 |
| BAX | BCL2-associated X protein | 3.13737 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.09477 |
| TCTA | T-cell leukemia translocation altered | 3.09308 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.96233 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.92434 |
| TPD52L2 | tumor protein D52-like 2 | 2.75264 |
| KIF20A | kinesin family member 20A | 2.57224 |
| RRAGA | Ras-related GTP binding A | 2.56645 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 2.49436 |
| GPATCH8 | G patch domain containing 8 | 2.4101 |
| ZNF274 | zinc finger protein 274 | 2.34464 |
| WDR70 | WD repeat domain 70 | 2.33593 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.3312 |
| FZD7 | frizzled class receptor 7 | 2.31734 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.31428 |
| HDGFL3 | HDGF like 3 | 2.29806 |
| PRR15L | proline rich 15-like | 2.22493 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.2179 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.2156 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 2.21477 |
| TRAP1 | TNF receptor-associated protein 1 | 2.21189 |
| COG4 | component of oligomeric golgi complex 4 | 2.20417 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 2.20127 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 2.17648 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.05916 |
| MMP2 | matrix metallopeptidase 2 | 2.03037 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | 2.02456 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 | 2.0159 |
| DROSHA | drosha, ribonuclease type III | 2.00385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.11747 |
| CD320 | CD320 molecule | -5.02279 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -4.85502 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.46499 |
| ZW10 | zw10 kinetochore protein | -3.41735 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -3.40149 |
| EGF | epidermal growth factor | -3.20255 |
| SLC35F2 | solute carrier family 35, member F2 | -3.18764 |
| WASHC4 | WASH complex subunit 4 | -3.12507 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.07184 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.03147 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.88718 |
| EBNA1BP2 | EBNA1 binding protein 2 | -2.79088 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.76497 |
| CAB39 | calcium binding protein 39 | -2.48779 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.47183 |
| SCAND1 | SCAN domain containing 1 | -2.43623 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.36151 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.32242 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.28836 |
| GNAS | GNAS complex locus | -2.26481 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.23548 |
| ELAC2 | elaC ribonuclease Z 2 | -2.21417 |
| TCTN1 | tectonic family member 1 | -2.17784 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.15822 |
| CTC1 | CTS telomere maintenance complex component 1 | -2.09528 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.0448 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.04132 |
| SESN1 | sestrin 1 | -2.01765 |
| MTFR1 | mitochondrial fission regulator 1 | -2.01307 |
