CRCGN013_HEPG2_24H:O11 Gene Set
Genes
52 genes differentially expressed following the CRCGN013_HEPG2_24H:O11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
5.86245
|
|
MAP7
|
microtubule-associated protein 7
|
5.44202
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
4.95119
|
|
GATA3
|
GATA binding protein 3
|
4.2734
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.19862
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.16194
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.07958
|
|
CHN1
|
chimerin 1
|
3.91519
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.57323
|
|
EGF
|
epidermal growth factor
|
3.20529
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.05058
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.70336
|
|
PRR15L
|
proline rich 15-like
|
2.54674
|
|
MGST2
|
microsomal glutathione S-transferase 2
|
2.47601
|
|
CCNA1
|
cyclin A1
|
2.46741
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.36633
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.3182
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.26351
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.25636
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.25586
|
|
PCDH12
|
protocadherin 12
|
2.2541
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.2238
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.16389
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.07692
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.02126
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.02042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.77127
|
|
LDHD
|
lactate dehydrogenase D
|
-5.64094
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.45333
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.76455
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.51328
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.37099
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.36306
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.34715
|
|
GNAS
|
GNAS complex locus
|
-3.98478
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.98461
|
|
FHL2
|
four and a half LIM domains 2
|
-3.93512
|
|
WASHC4
|
WASH complex subunit 4
|
-3.46897
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.41632
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.3127
|
|
PIK3R4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
-3.27319
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.86012
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.7257
|
|
GRN
|
granulin
|
-2.60082
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
-2.42701
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.29431
|
|
CCNB1
|
cyclin B1
|
-2.2484
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.19655
|
|
LIG4
|
ligase IV, DNA, ATP-dependent
|
-2.12328
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.05926
|
|
MLYCD
|
malonyl-CoA decarboxylase
|
-2.03217
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.00912
|
