CRCGN013_HEPG2_24H:O13 Gene Set
Genes
38 genes differentially expressed following the CRCGN013_HEPG2_24H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
6.83947
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.60743
|
|
CYCS
|
cytochrome c, somatic
|
4.32296
|
|
STK10
|
serine/threonine kinase 10
|
3.79284
|
|
LCN2
|
lipocalin 2
|
3.76142
|
|
E2F2
|
E2F transcription factor 2
|
3.64269
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.48083
|
|
CDC45
|
cell division cycle 45
|
3.17205
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.99472
|
|
MYLK
|
myosin light chain kinase
|
2.98654
|
|
GATA3
|
GATA binding protein 3
|
2.87924
|
|
PRR15L
|
proline rich 15-like
|
2.598
|
|
MOK
|
MOK protein kinase
|
2.59192
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.50996
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.38604
|
|
KIFBP
|
kinesin family binding protein
|
2.23991
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.21373
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.09903
|
|
CTSL
|
cathepsin L
|
2.07892
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.05181
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.04237
|
|
UTP18
|
UTP18 small subunit (SSU) processome component homolog (yeast)
|
2.03598
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-4.46804
|
|
CDC20
|
cell division cycle 20
|
-4.22876
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-3.5253
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.25288
|
|
LDHD
|
lactate dehydrogenase D
|
-3.08346
|
|
PSMG1
|
proteasome (prosome, macropain) assembly chaperone 1
|
-3.02251
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.95331
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.95176
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.63229
|
|
EGF
|
epidermal growth factor
|
-2.62406
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.50155
|
|
AURKB
|
aurora kinase B
|
-2.48599
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.37769
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.21256
|
|
HEBP1
|
heme binding protein 1
|
-2.12381
|
|
RAI14
|
retinoic acid induced 14
|
-2.02494
|
