CRCGN013_HEPG2_24H:O15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dieldrin 10.15 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 3.96937
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.67416
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.25385
SKIC2 SKI2 subunit of superkiller complex 3.09801
EPHA3 EPH receptor A3 2.90775
CHMP6 charged multivesicular body protein 6 2.43509
EGF epidermal growth factor 2.42955
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.33901
NES nestin 2.18763
NPDC1 neural proliferation, differentiation and control, 1 2.18352
KIF20A kinesin family member 20A 2.17765
TIAM1 T-cell lymphoma invasion and metastasis 1 2.08419
CDC45 cell division cycle 45 2.06425
CD93 CD93 molecule 2.03178

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -6.03075
CCNB2 cyclin B2 -3.8912
ZNF586 zinc finger protein 586 -3.73096
TNIP1 TNFAIP3 interacting protein 1 -3.3361
CDC20 cell division cycle 20 -3.29665
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.14441
BLCAP bladder cancer associated protein -3.14171
TCTN1 tectonic family member 1 -3.14045
DERA deoxyribose-phosphate aldolase (putative) -2.89401
FASTKD5 FAST kinase domains 5 -2.77183
GNAS GNAS complex locus -2.73116
ADI1 acireductone dioxygenase 1 -2.70238
HLA-DMA major histocompatibility complex, class II, DM alpha -2.61485
TXNDC9 thioredoxin domain containing 9 -2.5522
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.54818
CRELD2 cysteine-rich with EGF-like domains 2 -2.48785
FAIM Fas apoptotic inhibitory molecule -2.42872
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.25548
IFRD2 interferon-related developmental regulator 2 -2.21894
UBE3C ubiquitin protein ligase E3C -2.18558
WASHC4 WASH complex subunit 4 -2.18245