CRCGN013_HEPG2_24H:O16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dieldrin 5.07 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN013_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOTCH1 notch 1 6.58106
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.85898
CHN1 chimerin 1 4.56464
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 4.06961
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.82804
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.44636
PPARG peroxisome proliferator-activated receptor gamma 3.12555
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.00359
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.72351
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.16069
WDTC1 WD and tetratricopeptide repeats 1 2.07145

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -6.13711
GNAS GNAS complex locus -5.65819
ZNF586 zinc finger protein 586 -5.33223
RPN1 ribophorin I -4.72643
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.72062
MAP7 microtubule-associated protein 7 -3.40059
CD320 CD320 molecule -3.37052
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.1917
KDM3A lysine (K)-specific demethylase 3A -2.84243
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.60025
CCNB2 cyclin B2 -2.55826
EGF epidermal growth factor -2.55739
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.475
LOC124907782 dual specificity protein phosphatase 22 -2.38529
ANKRD36C ankyrin repeat domain 36C -2.24223
SLC35F2 solute carrier family 35, member F2 -2.20857
MRPS2 mitochondrial ribosomal protein S2 -2.18577
AURKB aurora kinase B -2.18308
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.17927
EHF ets homologous factor -2.1754
SEMG1 semenogelin I -2.1442
CHMP4B charged multivesicular body protein 4B -2.14336
ZNF280D zinc finger protein 280D -2.13994
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.07584
EIF5 eukaryotic translation initiation factor 5 -2.03912