CRCGN013_HEPG2_24H:O18 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.67157
|
|
TBP
|
TATA box binding protein
|
3.95813
|
|
NOTCH1
|
notch 1
|
3.5951
|
|
JADE2
|
jade family PHD finger 2
|
3.34902
|
|
RPL39L
|
ribosomal protein L39-like
|
3.3049
|
|
UBQLN2
|
ubiquilin 2
|
3.23531
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.01221
|
|
MYLK
|
myosin light chain kinase
|
3.01123
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.73467
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.68036
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.66684
|
|
E2F2
|
E2F transcription factor 2
|
2.58143
|
|
CCDC92
|
coiled-coil domain containing 92
|
2.53726
|
|
PTPN14
|
protein tyrosine phosphatase, non-receptor type 14
|
2.25133
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.09348
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.91511
|
|
CD320
|
CD320 molecule
|
-6.80002
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.83594
|
|
CCNB1
|
cyclin B1
|
-5.13701
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.07796
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.77547
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.71547
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.70797
|
|
THAP11
|
THAP domain containing 11
|
-3.64334
|
|
DNM1L
|
dynamin 1-like
|
-3.31865
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-3.28655
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.91176
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.86499
|
|
GNAS
|
GNAS complex locus
|
-2.83992
|
|
GRN
|
granulin
|
-2.52133
|
|
NOX1
|
NADPH oxidase 1
|
-2.46726
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.37301
|
|
EGF
|
epidermal growth factor
|
-2.30725
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.23981
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.23907
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.22663
|
|
ZNF586
|
zinc finger protein 586
|
-2.09092
|
|
PADI1
|
peptidyl arginine deiminase, type I
|
-2.07688
|
|
PSENEN
|
presenilin enhancer gamma secretase subunit
|
-2.06913
|
|
NUP85
|
nucleoporin 85kDa
|
-2.06479
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.02821
|
|
TBCB
|
tubulin folding cofactor B
|
-2.01612
|
