CRCGN013_HEPG2_24H:O19 Gene Set
Genes
38 genes differentially expressed following the CRCGN013_HEPG2_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
4.24883
|
|
MEF2C
|
myocyte enhancer factor 2C
|
3.38716
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.37931
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.16374
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.12283
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.61052
|
|
MAPKAPK2
|
mitogen-activated protein kinase-activated protein kinase 2
|
2.52361
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.46608
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.41504
|
|
SFTPB
|
surfactant protein B
|
2.30438
|
|
CHN1
|
chimerin 1
|
2.30235
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.23288
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.1742
|
|
SLC35E2B
|
solute carrier family 35, member E2B
|
2.09965
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.08678
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.03989
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.56
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.46052
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.31462
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.29593
|
|
CD320
|
CD320 molecule
|
-4.06582
|
|
PIK3R4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
-3.66995
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.61784
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-3.45313
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-3.35021
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.20441
|
|
CAB39
|
calcium binding protein 39
|
-3.07994
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.05037
|
|
RPS5
|
ribosomal protein S5
|
-2.96608
|
|
PEG10
|
paternally expressed 10
|
-2.80033
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.44298
|
|
ZW10
|
zw10 kinetochore protein
|
-2.42885
|
|
GNAS
|
GNAS complex locus
|
-2.21653
|
|
TCTN1
|
tectonic family member 1
|
-2.19401
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.17557
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.17439
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.15848
|
|
TEX10
|
testis expressed 10
|
-2.14661
|