CRCGN013_HEPG2_24H:O20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 10.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

36 genes differentially expressed following the CRCGN013_HEPG2_24H:O20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.27435
LCN2 lipocalin 2 5.04251
UBQLN2 ubiquilin 2 4.25659
MAP7 microtubule-associated protein 7 4.04315
NOSIP nitric oxide synthase interacting protein 2.81056
ADAT1 adenosine deaminase, tRNA-specific 1 2.6911
PPARG peroxisome proliferator-activated receptor gamma 2.65692
HDGFL3 HDGF like 3 2.5563
STIMATE STIM activating enhancer 2.55165
ADGRE5 adhesion G protein-coupled receptor E5 2.50237
PMM2 phosphomannomutase 2 2.42966
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.24861
HLA-DRA major histocompatibility complex, class II, DR alpha 2.15647
GPER1 G protein-coupled estrogen receptor 1 2.1431
KIF20A kinesin family member 20A 2.13491
CHMP6 charged multivesicular body protein 6 2.01727

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -6.28595
GNAS GNAS complex locus -5.00221
MAPK13 mitogen-activated protein kinase 13 -4.76894
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.63637
TLCD3A TLC domain containing 3A -3.55528
NUP85 nucleoporin 85kDa -3.37201
MRPS2 mitochondrial ribosomal protein S2 -3.08183
OXA1L oxidase (cytochrome c) assembly 1-like -2.9036
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.86934
ZNF586 zinc finger protein 586 -2.76714
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.67672
EXT1 exostosin glycosyltransferase 1 -2.60048
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.37414
RPIA ribose 5-phosphate isomerase A -2.33375
UBE2O ubiquitin-conjugating enzyme E2O -2.30012
KCTD2 potassium channel tetramerization domain containing 2 -2.2021
HEATR1 HEAT repeat containing 1 -2.17122
EGF epidermal growth factor -2.14255
MRPS7 mitochondrial ribosomal protein S7 -2.11299
HLA-DMA major histocompatibility complex, class II, DM alpha -2.10501