CRCGN013_HEPG2_24H:O21 Gene Set
Genes
37 genes differentially expressed following the CRCGN013_HEPG2_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.5365
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.31096
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.20888
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.80283
|
|
NOTCH1
|
notch 1
|
3.49071
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.18405
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.12895
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.09313
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.02815
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.83985
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.82278
|
|
STIMATE
|
STIM activating enhancer
|
2.41166
|
|
KIF20A
|
kinesin family member 20A
|
2.31213
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.25987
|
|
GATA2
|
GATA binding protein 2
|
2.23165
|
|
EPN2
|
epsin 2
|
2.13345
|
|
EVL
|
Enah/Vasp-like
|
2.09078
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.01415
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.19193
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.23881
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-4.23762
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.09099
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.60898
|
|
CDC20
|
cell division cycle 20
|
-3.59314
|
|
VAT1
|
vesicle amine transport 1
|
-3.55865
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.3023
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.20128
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.04785
|
|
LDHD
|
lactate dehydrogenase D
|
-3.02875
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.85679
|
|
GNAS
|
GNAS complex locus
|
-2.6817
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.62727
|
|
EGF
|
epidermal growth factor
|
-2.27492
|
|
CCNB2
|
cyclin B2
|
-2.1112
|
|
CCNB1
|
cyclin B1
|
-2.06214
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.04246
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.00368
|
