CRCGN013_HEPG2_24H:O23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (e)-3h-indol-3-ylidenemethanol 1.32 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN013_HEPG2_24H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 5.05194
SNAP25 synaptosomal-associated protein, 25kDa 4.41549
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.69192
UBQLN2 ubiquilin 2 3.63795
MAP7 microtubule-associated protein 7 2.96504
ADAT1 adenosine deaminase, tRNA-specific 1 2.75563
PROS1 protein S (alpha) 2.75417
CHN1 chimerin 1 2.65375
HYOU1 hypoxia up-regulated 1 2.57436
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.44943
LOC122526780 uncharacterized LOC122526780 2.11948

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -5.16575
UGDH UDP-glucose 6-dehydrogenase -4.67347
DNM1L dynamin 1-like -4.18467
EGF epidermal growth factor -4.0464
C2CD5 C2 calcium-dependent domain containing 5 -3.5654
FASTKD5 FAST kinase domains 5 -3.37168
ZDHHC6 zinc finger, DHHC-type containing 6 -3.2887
NRIP1 nuclear receptor interacting protein 1 -3.21103
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.95584
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.95494
TM9SF3 transmembrane 9 superfamily member 3 -2.91065
MAPK13 mitogen-activated protein kinase 13 -2.468
TNIP1 TNFAIP3 interacting protein 1 -2.43908
VDAC1 voltage-dependent anion channel 1 -2.15625
RFC2 replication factor C (activator 1) 2, 40kDa -2.09472