CRCGN013_HEPG2_24H:O24 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.83939
|
|
GPATCH8
|
G patch domain containing 8
|
4.53633
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.87186
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.52638
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.49783
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.17619
|
|
UBQLN2
|
ubiquilin 2
|
3.11524
|
|
STIMATE
|
STIM activating enhancer
|
3.09988
|
|
SFTPB
|
surfactant protein B
|
3.02741
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.87619
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.87321
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.74893
|
|
TBP
|
TATA box binding protein
|
2.67328
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.62748
|
|
HOXA10
|
homeobox A10
|
2.53213
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.30867
|
|
RRAGA
|
Ras-related GTP binding A
|
2.28133
|
|
COX7A2
|
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
|
2.26165
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.2243
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.10972
|
|
ITGA9
|
integrin, alpha 9
|
2.10097
|
|
NR2C2
|
nuclear receptor subfamily 2, group C, member 2
|
2.04144
|
|
NTAQ1
|
N-terminal glutamine amidase 1
|
2.0321
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.0221
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.00099
|
|
LDHD
|
lactate dehydrogenase D
|
-7.62551
|
|
CDC20
|
cell division cycle 20
|
-6.17311
|
|
CCNB1
|
cyclin B1
|
-3.95248
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.7278
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.56715
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.11372
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.71027
|
|
EGF
|
epidermal growth factor
|
-2.67612
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.5837
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.46082
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.43524
|
|
ADGRG2
|
adhesion G protein-coupled receptor G2
|
-2.32146
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.31683
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.31608
|
|
ASPA
|
aspartoacylase
|
-2.18476
|
|
RPS5
|
ribosomal protein S5
|
-2.11002
|
