CRCGN013_HEPG2_24H:P03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description disulfiram 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

518 genes differentially expressed following the CRCGN013_HEPG2_24H:P03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 6.49947
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.47628
E2F2 E2F transcription factor 2 6.18491
CHN1 chimerin 1 6.09008
MUC1 mucin 1, cell surface associated 5.64832
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.59518
TIAM1 T-cell lymphoma invasion and metastasis 1 5.57592
SSBP2 single-stranded DNA binding protein 2 5.28216
CBR3 carbonyl reductase 3 4.90657
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.74753
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 4.60735
SLC75A1 solute carrier family 75 member 1 4.52999
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 4.5091
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.33309
LSR lipolysis stimulated lipoprotein receptor 4.31674
MINDY1 MINDY lysine 48 deubiquitinase 1 4.25933
MAP7 microtubule-associated protein 7 4.09562
HLA-DMA major histocompatibility complex, class II, DM alpha 4.07558
LCN2 lipocalin 2 4.07042
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 4.05466
MVP major vault protein 3.97043
CAPN1 calpain 1, (mu/I) large subunit 3.95806
PCDHB11 protocadherin beta 11 3.88256
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.77714
PRKCD protein kinase C, delta 3.77055
CYCS cytochrome c, somatic 3.71495
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.63958
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 3.56755
ZNF589 zinc finger protein 589 3.50063
SFTPB surfactant protein B 3.49947
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.49562
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.43483
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 3.42947
HMG20B high mobility group 20B 3.40743
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 3.34219
SLC35F6 solute carrier family 35, member F6 3.34201
CBR1 carbonyl reductase 1 3.31868
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.30898
BACE2 beta-site APP-cleaving enzyme 2 3.30493
TAC4 tachykinin 4 (hemokinin) 3.28556
ITGB8 integrin, beta 8 3.25425
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 3.24075
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 3.23651
C2CD2 C2 calcium-dependent domain containing 2 3.22744
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.20311
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.20052
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.19933
DUSP4 dual specificity phosphatase 4 3.19381
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.14866
MYLK myosin light chain kinase 3.13162
KLHL9 kelch-like family member 9 3.11929
CNPY3 canopy FGF signaling regulator 3 3.11434
KLC3 kinesin light chain 3 3.09328
PSG5 pregnancy specific beta-1-glycoprotein 5 3.01207
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.99299
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.98413
MC4R melanocortin 4 receptor 2.96174
CSK c-src tyrosine kinase 2.96111
NANOS3 nanos homolog 3 (Drosophila) 2.95743
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.92099
ZDHHC24 zinc finger, DHHC-type containing 24 2.91801
MYOT myotilin 2.91067
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.90971
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.90568
EGF epidermal growth factor 2.89695
NBEAL2 neurobeachin-like 2 2.89665
NENF neudesin neurotrophic factor 2.89139
NYNRIN NYN domain and retroviral integrase containing 2.87651
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 2.85092
CPAP centrosome assembly and centriole elongation protein 2.84472
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.84358
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.84123
MCHR1 melanin-concentrating hormone receptor 1 2.83425
FFAR2 free fatty acid receptor 2 2.82685
FAM3C family with sequence similarity 3, member C 2.81989
IL19 interleukin 19 2.81623
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.80918
RRAGA Ras-related GTP binding A 2.80772
MEIS1 Meis homeobox 1 2.78856
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.77299
NOCT nocturnin 2.76875
IL12A interleukin 12A 2.76813
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.76187
FBXO40 F-box protein 40 2.75309
TCHH trichohyalin 2.74953
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 2.73892
PRAF2 PRA1 domain family, member 2 2.72935
BDKRB2 bradykinin receptor B2 2.72632
PSG6 pregnancy specific beta-1-glycoprotein 6 2.72011
SLC46A3 solute carrier family 46, member 3 2.71983
PARP2 poly (ADP-ribose) polymerase 2 2.7052
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.7046
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.70174
HSPB2 heat shock 27kDa protein 2 2.70016
SLIT2 slit homolog 2 (Drosophila) 2.69571
CABP5 calcium binding protein 5 2.69407
TRPM3 transient receptor potential cation channel, subfamily M, member 3 2.68894
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.67221
MTCL1 microtubule crosslinking factor 1 2.66963
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.66821
LTA lymphotoxin alpha 2.66149
DDR1 discoidin domain receptor tyrosine kinase 1 2.6595
TCTA T-cell leukemia translocation altered 2.65483
DGKG diacylglycerol kinase, gamma 90kDa 2.65472
DNM1 dynamin 1 2.65124
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.64106
BMP15 bone morphogenetic protein 15 2.63156
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.62173
RCVRN recoverin 2.60524
ERMP1 endoplasmic reticulum metallopeptidase 1 2.6033
CTSF cathepsin F 2.5865
ADAT1 adenosine deaminase, tRNA-specific 1 2.57322
CBLN1 cerebellin 1 precursor 2.56923
TMEM109 transmembrane protein 109 2.56838
MAEA macrophage erythroblast attacher 2.5679
TFEB transcription factor EB 2.56609
RSRC1 arginine/serine-rich coiled-coil 1 2.56534
POMP proteasome maturation protein 2.55686
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.55479
PVALB parvalbumin 2.54985
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.54738
DCLRE1C DNA cross-link repair 1C 2.54539
PRDM5 PR domain containing 5 2.53996
CASQ2 calsequestrin 2 (cardiac muscle) 2.53934
RABAC1 Rab acceptor 1 (prenylated) 2.52807
ACP6 acid phosphatase 6, lysophosphatidic 2.528
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.522
NXPH3 neurexophilin 3 2.51982
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.51967
AP5M1 adaptor-related protein complex 5, mu 1 subunit 2.51863
KRI1 KRI1 homolog (S. cerevisiae) 2.51815
RPP38 ribonuclease P/MRP 38kDa subunit 2.51814
ZFP37 ZFP37 zinc finger protein 2.51572
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 2.50444
ADRB2 adrenoceptor beta 2, surface 2.50293
ZNF282 zinc finger protein 282 2.49523
FOXO3 forkhead box O3 2.4949
FAT2 FAT atypical cadherin 2 2.49304
MFAP5 microfibrillar associated protein 5 2.49281
VN1R1 vomeronasal 1 receptor 1 2.49016
MED31 mediator complex subunit 31 2.48957
GSTA4 glutathione S-transferase alpha 4 2.4879
GOLGA6L9 golgin A6 family-like 9 2.48513
TBX4 T-box 4 2.48169
TBC1D31 TBC1 domain family, member 31 2.47365
IRF5 interferon regulatory factor 5 2.47228
DRC4 dynein regulatory complex subunit 4 2.46556
SCAF4 SR-related CTD-associated factor 4 2.45512
KRT33A keratin 33A, type I 2.44993
IFNA21 interferon, alpha 21 2.44914
ZNF862 zinc finger protein 862 2.44857
WNT2 wingless-type MMTV integration site family member 2 2.44816
PRKCE protein kinase C, epsilon 2.44397
RBMS3 RNA binding motif, single stranded interacting protein 3 2.43891
ZNF669 zinc finger protein 669 2.43535
FSHR follicle stimulating hormone receptor 2.43405
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.43057
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.42861
MTMR10 myotubularin related protein 10 2.42792
DENR density-regulated protein 2.42735
SPATA31A3 SPATA31 subfamily A, member 3 2.42687
LRRC32 leucine rich repeat containing 32 2.42664
SQOR sulfide quinone oxidoreductase 2.42245
EHD1 EH-domain containing 1 2.42125
AOC2 amine oxidase, copper containing 2 (retina-specific) 2.41591
FASTK Fas-activated serine/threonine kinase 2.41421
TMEM120B transmembrane protein 120B 2.41312
CROT carnitine O-octanoyltransferase 2.41164
REEP4 receptor accessory protein 4 2.40652
KRT34 keratin 34, type I 2.40555
CCDC177 coiled-coil domain containing 177 2.40318
GCC1 GRIP and coiled-coil domain containing 1 2.39975
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.39722
ANKRD34C ankyrin repeat domain 34C 2.39538
HOXB6 homeobox B6 2.39512
CYFIP2 cytoplasmic FMR1 interacting protein 2 2.39077
TBC1D10C TBC1 domain family, member 10C 2.38957
IHH indian hedgehog 2.38888
NCR3 natural cytotoxicity triggering receptor 3 2.38767
PRSS50 protease, serine, 50 2.37864
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.37672
UBE2M ubiquitin-conjugating enzyme E2M 2.3763
STK25 serine/threonine kinase 25 2.36794
MTA2 metastasis associated 1 family, member 2 2.35464
BCO1 beta-carotene oxygenase 1 2.35325
AKAP8L A kinase (PRKA) anchor protein 8-like 2.34956
ZMYM5 zinc finger, MYM-type 5 2.34801
HOXA10 homeobox A10 2.3459
JAM2 junctional adhesion molecule 2 2.34134
APOL5 apolipoprotein L, 5 2.32873
RANBP17 RAN binding protein 17 2.324
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 2.31977
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa 2.31973
CEP97 centrosomal protein 97kDa 2.31907
BAX BCL2-associated X protein 2.31486
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.31261
CTSL cathepsin L 2.31233
CHODL chondrolectin 2.30596
HOXB5 homeobox B5 2.30452
MYL2 myosin, light chain 2, regulatory, cardiac, slow 2.3041
TULP2 tubby like protein 2 2.29874
TMSB4X thymosin beta 4, X-linked 2.29678
AKTIP AKT interacting protein 2.29131
H2BC21 H2B clustered histone 21 2.28925
LSP1 lymphocyte-specific protein 1 2.28912
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 2.28849
BLVRA biliverdin reductase A 2.28473
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 2.28408
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.28202
COL19A1 collagen, type XIX, alpha 1 2.27959
ABHD4 abhydrolase domain containing 4 2.27421
GSTP1 glutathione S-transferase pi 1 2.27121
HSPB3 heat shock 27kDa protein 3 2.26795
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.26697
SLAMF1 signaling lymphocytic activation molecule family member 1 2.26378
IFNA7 interferon, alpha 7 2.26303
SSTR4 somatostatin receptor 4 2.26297
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.26234
MAGEC2 melanoma antigen family C2 2.26101
TPM3 tropomyosin 3 2.26057
DEFB126 defensin, beta 126 2.25921
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.25879
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 2.25763
SPRED2 sprouty-related, EVH1 domain containing 2 2.25398
ARHGAP28 Rho GTPase activating protein 28 2.24491
PSG2 pregnancy specific beta-1-glycoprotein 2 2.24354
CIBAR1 CBY1 interacting BAR domain containing 1 2.24299
DOCK5 dedicator of cytokinesis 5 2.24009
CETN1 centrin, EF-hand protein, 1 2.23753
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 2.23707
PIH1D1 PIH1 domain containing 1 2.23575
MSH4 mutS homolog 4 2.23464
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.23444
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.23379
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 2.2336
INPP1 inositol polyphosphate-1-phosphatase 2.23301
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.23081
SIGLEC5 sialic acid binding Ig-like lectin 5 2.22852
POM121L2 POM121 transmembrane nucleoporin-like 2 2.22725
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.22512
GYPC glycophorin C (Gerbich blood group) 2.22452
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.22432
EHBP1L1 EH domain binding protein 1-like 1 2.22319
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.22088
ADORA3 adenosine A3 receptor 2.21959
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.21934
S100A14 S100 calcium binding protein A14 2.21865
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.21707
ADAM2 ADAM metallopeptidase domain 2 2.21285
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like 2.21285
DPT dermatopontin 2.20894
BLMH bleomycin hydrolase 2.20713
CCDC7 coiled-coil domain containing 7 2.20377
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.20237
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.20002
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.1995
FBLN2 fibulin 2 2.19632
TREM1 triggering receptor expressed on myeloid cells 1 2.19515
FXYD1 FXYD domain containing ion transport regulator 1 2.19465
NOX3 NADPH oxidase 3 2.1917
CHRM5 cholinergic receptor, muscarinic 5 2.19163
RETREG1 reticulophagy regulator 1 2.18912
MFAP4 microfibrillar-associated protein 4 2.1885
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.18438
MOK MOK protein kinase 2.18338
CA10 carbonic anhydrase X 2.18279
EVC Ellis van Creveld protein 2.18241
DCAF13 DDB1 and CUL4 associated factor 13 2.17678
KLHL41 kelch-like family member 41 2.17294
COQ8B coenzyme Q8B 2.17229
PAMR1 peptidase domain containing associated with muscle regeneration 1 2.16933
RDH8 retinol dehydrogenase 8 (all-trans) 2.16726
KRT33B keratin 33B, type I 2.16137
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.15997
KRT9 keratin 9, type I 2.15652
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 2.15499
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.15454
FGF9 fibroblast growth factor 9 2.15188
CLDN9 claudin 9 2.15163
BARX2 BARX homeobox 2 2.14984
ADAM20 ADAM metallopeptidase domain 20 2.1498
PRPF18 pre-mRNA processing factor 18 2.14852
TMEM168 transmembrane protein 168 2.14821
HOXB2 homeobox B2 2.14438
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.14349
CASS4 Cas scaffolding protein family member 4 2.13973
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 2.13961
HOXB8 homeobox B8 2.13929
SPATA6 spermatogenesis associated 6 2.13758
TEP1 telomerase-associated protein 1 2.13754
CHRM2 cholinergic receptor, muscarinic 2 2.1353
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.13495
SRPK3 SRSF protein kinase 3 2.13141
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 2.13078
GPER1 G protein-coupled estrogen receptor 1 2.12733
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.12731
ZNF197 zinc finger protein 197 2.12626
GATA2 GATA binding protein 2 2.12398
ANO10 anoctamin 10 2.12117
MOXD1 monooxygenase, DBH-like 1 2.12036
PRR15L proline rich 15-like 2.1203
MAP1B microtubule-associated protein 1B 2.11644
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.11418
BRCA1 breast cancer 1, early onset 2.11322
KLHL29 kelch-like family member 29 2.11233
POPDC2 popeye domain containing 2 2.10848
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 2.10636
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.10234
TAS2R13 taste receptor, type 2, member 13 2.09559
ADAM29 ADAM metallopeptidase domain 29 2.09494
SAP18 Sin3A-associated protein, 18kDa 2.09445
SMCP sperm mitochondria-associated cysteine-rich protein 2.09427
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.09336
CTF1 cardiotrophin 1 2.09278
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.09196
AKAP3 A kinase (PRKA) anchor protein 3 2.09054
SYNPO2L synaptopodin 2-like 2.09025
SNED1 sushi, nidogen and EGF-like domains 1 2.08355
SMR3A submaxillary gland androgen regulated protein 3A 2.08001
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 2.07848
KRT36 keratin 36, type I 2.07773
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.07537
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 2.07469
CDK7 cyclin-dependent kinase 7 2.07088
ZNF507 zinc finger protein 507 2.06682
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.06639
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 2.06432
HELZ helicase with zinc finger 2.06397
HID1 HID1 domain containing 2.0633
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.06096
CREB3L1 cAMP responsive element binding protein 3-like 1 2.06079
NEK7 NIMA-related kinase 7 2.05856
ATP5PF ATP synthase peripheral stalk subunit F6 2.05516
NRIP2 nuclear receptor interacting protein 2 2.05245
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.05211
SASH3 SAM and SH3 domain containing 3 2.052
SIRPG signal-regulatory protein gamma 2.05086
KRTAP2-3 keratin associated protein 2-3 2.05035
OXCT1 3-oxoacid CoA transferase 1 2.04404
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 2.04117
KLF6 Kruppel-like factor 6 2.03788
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 2.03781
MAGEA8 melanoma antigen family A8 2.03638
ZNF407 zinc finger protein 407 2.03495
EFNA2 ephrin-A2 2.03315
SHH sonic hedgehog 2.03204
EFNA5 ephrin-A5 2.03079
PRKX protein kinase, X-linked 2.0275
MINDY3 MINDY lysine 48 deubiquitinase 3 2.0273
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.02622
ADPRH ADP-ribosylarginine hydrolase 2.02406
MC5R melanocortin 5 receptor 2.02286
CREB5 cAMP responsive element binding protein 5 2.02255
DKK2 dickkopf WNT signaling pathway inhibitor 2 2.02243
MOSPD3 motile sperm domain containing 3 2.02057
CYB5R2 cytochrome b5 reductase 2 2.02042
DENND2A DENN/MADD domain containing 2A 2.0199
CASZ1 castor zinc finger 1 2.01754
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.0162
VGLL3 vestigial-like family member 3 2.01043
MELTF melanotransferrin 2.0076
ZDHHC11B zinc finger, DHHC-type containing 11B 2.00475
ZFP91 ZFP91 zinc finger protein 2.0047
FGF1 fibroblast growth factor 1 (acidic) 2.00222
TSPAN9 tetraspanin 9 2.00194

decreased expression

Symbol Name Standardized Value
THAP11 THAP domain containing 11 -8.37314
C5 complement component 5 -7.89937
FAIM Fas apoptotic inhibitory molecule -6.82718
CDC20 cell division cycle 20 -6.30774
PECR peroxisomal trans-2-enoyl-CoA reductase -6.29035
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -6.21367
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -5.69526
TCTN1 tectonic family member 1 -5.59613
COG4 component of oligomeric golgi complex 4 -5.03687
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -4.85234
KDM3A lysine (K)-specific demethylase 3A -4.84537
PTPRK protein tyrosine phosphatase, receptor type, K -4.82
RGS2 regulator of G-protein signaling 2 -4.75443
EAPP E2F-associated phosphoprotein -4.57091
ZMIZ1 zinc finger, MIZ-type containing 1 -4.40486
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.36958
NGRN neugrin, neurite outgrowth associated -4.32119
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -4.22323
LRRC47 leucine rich repeat containing 47 -4.15395
HSPA1A heat shock 70kDa protein 1A -4.13196
SOAT2 sterol O-acyltransferase 2 -4.01297
ARID5B AT rich interactive domain 5B (MRF1-like) -4.00836
CRELD2 cysteine-rich with EGF-like domains 2 -3.99033
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.9497
MTFR1 mitochondrial fission regulator 1 -3.90472
PRCP prolylcarboxypeptidase (angiotensinase C) -3.89186
UBE2C ubiquitin-conjugating enzyme E2C -3.87854
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.73241
ETFB electron-transfer-flavoprotein, beta polypeptide -3.70719
NUP93 nucleoporin 93kDa -3.67397
HAT1 histone acetyltransferase 1 -3.65257
TCERG1 transcription elongation regulator 1 -3.49836
PSRC1 proline/serine-rich coiled-coil 1 -3.42549
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.382
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -3.36846
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.2657
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.2086
DSG2 desmoglein 2 -3.20724
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.20637
SLC35E2B solute carrier family 35, member E2B -3.18225
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.16302
HDAC2 histone deacetylase 2 -3.06801
KLHL21 kelch-like family member 21 -3.0462
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.03164
AURKB aurora kinase B -3.00418
CALM3 calmodulin 3 (phosphorylase kinase, delta) -2.98576
APOE apolipoprotein E -2.85343
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.84342
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.83372
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.83007
MUTYH mutY homolog -2.8095
ZNF274 zinc finger protein 274 -2.7476
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.74481
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.74258
SLC35F2 solute carrier family 35, member F2 -2.72417
HPCA hippocalcin -2.71269
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.68448
HMGA2 high mobility group AT-hook 2 -2.68268
APOC3 apolipoprotein C-III -2.67355
RIDA reactive intermediate imine deaminase A homolog -2.65591
AHSG alpha-2-HS-glycoprotein -2.60873
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -2.60524
TMEM97 transmembrane protein 97 -2.59363
ALDOC aldolase C, fructose-bisphosphate -2.58148
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.57973
KCTD15 potassium channel tetramerization domain containing 15 -2.57155
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.52706
SF3A3 splicing factor 3a, subunit 3, 60kDa -2.52588
SMNDC1 survival motor neuron domain containing 1 -2.50616
PNRC1 proline-rich nuclear receptor coactivator 1 -2.50572
DCK deoxycytidine kinase -2.50261
SARAF store-operated calcium entry-associated regulatory factor -2.49684
DDN dendrin -2.49481
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -2.48006
YARS1 tyrosyl-tRNA synthetase 1 -2.47821
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.47767
ARID4A AT rich interactive domain 4A (RBP1-like) -2.47748
CAB39 calcium binding protein 39 -2.47163
ZC3H4 zinc finger CCCH-type containing 4 -2.46728
APOB apolipoprotein B -2.46468
HTRA1 HtrA serine peptidase 1 -2.46135
DDIT4 DNA-damage-inducible transcript 4 -2.45096
GSTM2 glutathione S-transferase mu 2 (muscle) -2.4402
AMBP alpha-1-microglobulin/bikunin precursor -2.43859
MRPS2 mitochondrial ribosomal protein S2 -2.42662
A1CF APOBEC1 complementation factor -2.42042
ELAC2 elaC ribonuclease Z 2 -2.41927
ORM1 orosomucoid 1 -2.39986
CIRBP cold inducible RNA binding protein -2.39894
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.39694
OXA1L oxidase (cytochrome c) assembly 1-like -2.36998
MAGED4B melanoma antigen family D4B -2.36416
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.34855
MRPL18 mitochondrial ribosomal protein L18 -2.34398
APOA1 apolipoprotein A-I -2.34381
IGFBP1 insulin-like growth factor binding protein 1 -2.34258
KIF14 kinesin family member 14 -2.33793
TCEAL4 transcription elongation factor A (SII)-like 4 -2.31466
MSMO1 methylsterol monooxygenase 1 -2.31009
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.30924
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.30738
HINFP histone H4 transcription factor -2.28472
DPH2 DPH2 homolog (S. cerevisiae) -2.28391
RPAP2 RNA polymerase II associated protein 2 -2.28313
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -2.27794
GCHFR GTP cyclohydrolase I feedback regulator -2.26739
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -2.26165
HDAC4 histone deacetylase 4 -2.25995
VAC14 Vac14 homolog (S. cerevisiae) -2.25648
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) -2.25299
TOPBP1 topoisomerase (DNA) II binding protein 1 -2.24543
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.23886
HPD 4-hydroxyphenylpyruvate dioxygenase -2.22641
FABP1 fatty acid binding protein 1, liver -2.22451
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.22371
ZNF593 zinc finger protein 593 -2.21277
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.21041
APOM apolipoprotein M -2.18549
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.18391
TOR4A torsin family 4, member A -2.17602
ISOC1 isochorismatase domain containing 1 -2.16161
ORM2 orosomucoid 2 -2.14404
NRGN neurogranin (protein kinase C substrate, RC3) -2.13953
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -2.13582
APOA2 apolipoprotein A-II -2.13555
GRB7 growth factor receptor-bound protein 7 -2.11766
APOH apolipoprotein H (beta-2-glycoprotein I) -2.11615
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -2.11378
PEX10 peroxisomal biogenesis factor 10 -2.11362
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.10925
MAT1A methionine adenosyltransferase I, alpha -2.10746
FGA fibrinogen alpha chain -2.09886
PLK1 polo-like kinase 1 -2.09174
JOSD1 Josephin domain containing 1 -2.08076
EXOSC8 exosome component 8 -2.07984
TGIF2 TGFB-induced factor homeobox 2 -2.07354
OSBPL11 oxysterol binding protein-like 11 -2.0641
MTTP microsomal triglyceride transfer protein -2.05994
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.05277
MVD mevalonate (diphospho) decarboxylase -2.05112
MCFD2 multiple coagulation factor deficiency 2 -2.0404
PDE2A phosphodiesterase 2A, cGMP-stimulated -2.04019
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.03895
WDR3 WD repeat domain 3 -2.03354
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 -2.02707
FN1 fibronectin 1 -2.02169
ZHX2 zinc fingers and homeoboxes 2 -2.0206
LOC102724560 cystathionine beta-synthase -2.01384
KDM8 lysine (K)-specific demethylase 8 -2.01235
ACY1 aminoacylase 1 -2.00918
STXBP2 syntaxin binding protein 2 -2.00719
ZFP36 ZFP36 ring finger protein -2.00439
RNF5 ring finger protein 5, E3 ubiquitin protein ligase -2.00409