| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | disulfiram 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN013_HEPG2_24H:P04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.95736 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.61144 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.26953 |
| MOK | MOK protein kinase | 4.13578 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.09741 |
| ABHD6 | abhydrolase domain containing 6 | 3.85493 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.278 |
| PRR15L | proline rich 15-like | 3.20954 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.11757 |
| TBP | TATA box binding protein | 3.10233 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.09702 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.89849 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.85627 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.75375 |
| LOC122526780 | uncharacterized LOC122526780 | 2.69211 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.55495 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.45518 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 2.38477 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.34663 |
| ZNF589 | zinc finger protein 589 | 2.31327 |
| TSPAN8 | tetraspanin 8 | 2.30879 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.21822 |
| MLPH | melanophilin | 2.16745 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 2.14742 |
| KLF10 | Kruppel-like factor 10 | 2.1467 |
| EGF | epidermal growth factor | 2.13742 |
| HDAC4 | histone deacetylase 4 | 2.10947 |
| ZNF518A | zinc finger protein 518A | 2.09863 |
| PARG | poly (ADP-ribose) glycohydrolase | 2.07278 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.07134 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.06976 |
| DNM1 | dynamin 1 | 2.05967 |
| RSBN1 | round spermatid basic protein 1 | 2.03823 |
| KLHL12 | kelch-like family member 12 | 2.00316 |
| BLCAP | bladder cancer associated protein | 2.00235 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAP3 | leucine aminopeptidase 3 | -7.78372 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.60164 |
| GTPBP8 | GTP-binding protein 8 (putative) | -6.51778 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -6.25334 |
| GNAS | GNAS complex locus | -5.68105 |
| LDHD | lactate dehydrogenase D | -5.64685 |
| PCNA | proliferating cell nuclear antigen | -4.55517 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.26515 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.17952 |
| NUP85 | nucleoporin 85kDa | -3.75705 |
| ADI1 | acireductone dioxygenase 1 | -3.45802 |
| TRIB3 | tribbles pseudokinase 3 | -3.43941 |
| CCNB1 | cyclin B1 | -3.11906 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.0106 |
| CCDC86 | coiled-coil domain containing 86 | -2.76618 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.64731 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.59044 |
| DNM1L | dynamin 1-like | -2.57008 |
| TCTN1 | tectonic family member 1 | -2.46706 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.46061 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.33101 |
| SLC35F2 | solute carrier family 35, member F2 | -2.20255 |
| TMPRSS5 | transmembrane protease, serine 5 | -2.18314 |
| NGRN | neugrin, neurite outgrowth associated | -2.18128 |
| SLBP | stem-loop binding protein | -2.15947 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -2.1538 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.1399 |
| PLAAT4 | phospholipase A and acyltransferase 4 | -2.06641 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 | -2.05465 |
| NXPH4 | neurexophilin 4 | -2.04573 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -2.02723 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | -2.01416 |
| LOC102725023 | killer cell immunoglobulin-like receptor 2DS3 allele 0020101 | -2.0102 |
