CRCGN013_HEPG2_24H:P07 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:P07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
3.34083
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.2943
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.22092
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.15769
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.02004
|
|
IDE
|
insulin-degrading enzyme
|
2.9478
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.88767
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.82269
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.80542
|
|
VGLL4
|
vestigial-like family member 4
|
2.77614
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.75088
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.74145
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.72184
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.37995
|
|
MAP3K2
|
mitogen-activated protein kinase kinase kinase 2
|
2.27793
|
|
LCE2B
|
late cornified envelope 2B
|
2.15359
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.1032
|
|
BAX
|
BCL2-associated X protein
|
2.10102
|
|
RCOR3
|
REST corepressor 3
|
2.08103
|
|
ZNF273
|
zinc finger protein 273
|
2.04278
|
|
TLR4
|
toll-like receptor 4
|
2.03609
|
|
LORICRIN
|
loricrin cornified envelope precursor protein
|
2.02882
|
|
KRT2
|
keratin 2, type II
|
2.01936
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.37865
|
|
MTA1
|
metastasis associated 1
|
-4.15255
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.10416
|
|
CCNB1
|
cyclin B1
|
-4.08358
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.04401
|
|
ZW10
|
zw10 kinetochore protein
|
-3.91678
|
|
PLK1
|
polo-like kinase 1
|
-3.90601
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-3.65536
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.53676
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.41615
|
|
GDF15
|
growth differentiation factor 15
|
-3.2845
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.16661
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.01995
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-3.00215
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.84829
|
|
EGF
|
epidermal growth factor
|
-2.82849
|
|
GNAS
|
GNAS complex locus
|
-2.81078
|
|
CCNB2
|
cyclin B2
|
-2.52509
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-2.52274
|
|
SCAND1
|
SCAN domain containing 1
|
-2.51366
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.40581
|
|
CAB39
|
calcium binding protein 39
|
-2.32447
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.22735
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.1907
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.18725
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.09963
|
|
ILK
|
integrin-linked kinase
|
-2.01482
|
