CRCGN013_HEPG2_24H:P08 Gene Set
Genes
49 genes differentially expressed following the CRCGN013_HEPG2_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.10713
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
7.4845
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
4.54963
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.36154
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.89415
|
|
NOTCH1
|
notch 1
|
3.88306
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.70134
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.66413
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.55257
|
|
EPHA3
|
EPH receptor A3
|
3.48399
|
|
CTSL
|
cathepsin L
|
2.92429
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.70534
|
|
GPATCH8
|
G patch domain containing 8
|
2.60505
|
|
SFTPB
|
surfactant protein B
|
2.59817
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.38595
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.34574
|
|
FLVCR2
|
feline leukemia virus subgroup C cellular receptor family, member 2
|
2.31778
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.25096
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.2123
|
|
CHN1
|
chimerin 1
|
2.19791
|
|
LCN2
|
lipocalin 2
|
2.0999
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.06097
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.72839
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.94478
|
|
ZNF586
|
zinc finger protein 586
|
-6.71186
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.03046
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.38333
|
|
VAT1
|
vesicle amine transport 1
|
-4.33305
|
|
CD320
|
CD320 molecule
|
-3.91342
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.81318
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.6605
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.57019
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.44358
|
|
MAP7
|
microtubule-associated protein 7
|
-3.42759
|
|
GNAS
|
GNAS complex locus
|
-2.97835
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.97419
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.92223
|
|
CCNB2
|
cyclin B2
|
-2.87202
|
|
PEG10
|
paternally expressed 10
|
-2.76832
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.69855
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.63981
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.257
|
|
ZNF134
|
zinc finger protein 134
|
-2.21952
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.21789
|
|
CAB39
|
calcium binding protein 39
|
-2.17701
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.15828
|
|
PPT2
|
palmitoyl-protein thioesterase 2
|
-2.05572
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.05132
|
|
FOLR3
|
folate receptor 3 (gamma)
|
-2.00769
|