CRCGN013_HEPG2_24H:P09 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.83822
|
|
MYLK
|
myosin light chain kinase
|
3.44038
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.30107
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.21311
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.10583
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.04595
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.9726
|
|
LCN2
|
lipocalin 2
|
2.90017
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.80362
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.7897
|
|
STIMATE
|
STIM activating enhancer
|
2.75233
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.67539
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.66199
|
|
MCOLN1
|
mucolipin 1
|
2.53372
|
|
PRR15L
|
proline rich 15-like
|
2.47801
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.31002
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.27794
|
|
TBP
|
TATA box binding protein
|
2.27622
|
|
BBX
|
bobby sox homolog (Drosophila)
|
2.0441
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.025
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-6.78705
|
|
GNAS
|
GNAS complex locus
|
-5.2114
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.08278
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.00289
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.99546
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.58676
|
|
CCNB1
|
cyclin B1
|
-3.43132
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.23471
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.16639
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.1289
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.7657
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.58672
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.57921
|
|
MAP7
|
microtubule-associated protein 7
|
-2.51997
|
|
NUP85
|
nucleoporin 85kDa
|
-2.42435
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.31171
|
|
RBM34
|
RNA binding motif protein 34
|
-2.26222
|
|
ATP13A2
|
ATPase type 13A2
|
-2.21061
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.1997
|
|
CHRM3
|
cholinergic receptor, muscarinic 3
|
-2.18232
|
|
SCAND1
|
SCAN domain containing 1
|
-2.15669
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.08203
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.05534
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.04505
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-2.02995
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.0041
|
