CRCGN013_HEPG2_24H:P13 Gene Set
Genes
38 genes differentially expressed following the CRCGN013_HEPG2_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.31156
|
|
RPL39L
|
ribosomal protein L39-like
|
4.3023
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.87203
|
|
HEBP1
|
heme binding protein 1
|
3.67706
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.52093
|
|
STIMATE
|
STIM activating enhancer
|
3.35087
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.15142
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.74035
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.69532
|
|
CTSL
|
cathepsin L
|
2.67177
|
|
GATA3
|
GATA binding protein 3
|
2.58547
|
|
KIF5C
|
kinesin family member 5C
|
2.38766
|
|
TBP
|
TATA box binding protein
|
2.30125
|
|
CYCS
|
cytochrome c, somatic
|
2.23359
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.09303
|
|
RRAGA
|
Ras-related GTP binding A
|
2.04081
|
|
CCNF
|
cyclin F
|
2.01808
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.23711
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.51474
|
|
GNAS
|
GNAS complex locus
|
-4.2991
|
|
NUP93
|
nucleoporin 93kDa
|
-4.17371
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.9881
|
|
CCNB1
|
cyclin B1
|
-3.83747
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.7657
|
|
LDHD
|
lactate dehydrogenase D
|
-3.41018
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.39453
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.37746
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.14048
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.96372
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.80669
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.53514
|
|
CCNB2
|
cyclin B2
|
-2.31573
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.27371
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.22766
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.14493
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
-2.10595
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.10176
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.00808
|