CRCGN013_HEPG2_24H:P13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 20.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN013_HEPG2_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 6.31156
RPL39L ribosomal protein L39-like 4.3023
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.87203
HEBP1 heme binding protein 1 3.67706
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.52093
STIMATE STIM activating enhancer 3.35087
ABHD6 abhydrolase domain containing 6 3.15142
PIH1D1 PIH1 domain containing 1 2.74035
ANO1 anoctamin 1, calcium activated chloride channel 2.69532
CTSL cathepsin L 2.67177
GATA3 GATA binding protein 3 2.58547
KIF5C kinesin family member 5C 2.38766
TBP TATA box binding protein 2.30125
CYCS cytochrome c, somatic 2.23359
LPAR2 lysophosphatidic acid receptor 2 2.09303
RRAGA Ras-related GTP binding A 2.04081
CCNF cyclin F 2.01808

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.23711
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.51474
GNAS GNAS complex locus -4.2991
NUP93 nucleoporin 93kDa -4.17371
NT5DC2 5'-nucleotidase domain containing 2 -3.9881
CCNB1 cyclin B1 -3.83747
PCCB propionyl CoA carboxylase, beta polypeptide -3.7657
LDHD lactate dehydrogenase D -3.41018
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.39453
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.37746
CCDC86 coiled-coil domain containing 86 -3.14048
ADI1 acireductone dioxygenase 1 -2.96372
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.80669
UBE3C ubiquitin protein ligase E3C -2.53514
CCNB2 cyclin B2 -2.31573
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.27371
TNIP1 TNFAIP3 interacting protein 1 -2.22766
MAPK13 mitogen-activated protein kinase 13 -2.14493
NLRP2B NLR family pyrin domain containing 2B -2.10595
PCNA proliferating cell nuclear antigen -2.10176
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.00808