CRCGN013_HEPG2_24H:P14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 10.13 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN013_HEPG2_24H:P14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 4.64385
RPP38 ribonuclease P/MRP 38kDa subunit 4.34742
ATP11B ATPase, class VI, type 11B 3.78938
MAP7 microtubule-associated protein 7 3.35177
CHN1 chimerin 1 3.32958
DIPK1A divergent protein kinase domain 1A 2.89562
MOK MOK protein kinase 2.68972
PLSCR3 phospholipid scramblase 3 2.42946
GPATCH8 G patch domain containing 8 2.39648
HOXA10 homeobox A10 2.37408
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.37349
INTS3 integrator complex subunit 3 2.3589
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.30654
CYCS cytochrome c, somatic 2.26154
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.07301
NOSIP nitric oxide synthase interacting protein 2.02617

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -5.4394
MAPK13 mitogen-activated protein kinase 13 -5.1675
LAP3 leucine aminopeptidase 3 -4.13864
GDF15 growth differentiation factor 15 -3.67803
CDC20 cell division cycle 20 -3.23303
CCNB1 cyclin B1 -3.12922
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.09891
KDM3A lysine (K)-specific demethylase 3A -3.09813
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.00921
PCNA proliferating cell nuclear antigen -2.9362
HMG20B high mobility group 20B -2.89312
DERA deoxyribose-phosphate aldolase (putative) -2.79919
ADI1 acireductone dioxygenase 1 -2.7429
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.72349
PEG10 paternally expressed 10 -2.65355
CD320 CD320 molecule -2.63582
LDHD lactate dehydrogenase D -2.4568
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.41182
NRIP1 nuclear receptor interacting protein 1 -2.22289
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.21909
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.06847
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.04987
PPY pancreatic polypeptide -2.01069