CRCGN013_HEPG2_24H:P15 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
9.18646
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
8.96012
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.0097
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.96535
|
|
GATA3
|
GATA binding protein 3
|
3.81716
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.75434
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.47055
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.8181
|
|
TLR4
|
toll-like receptor 4
|
2.69035
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.51972
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.48778
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.45611
|
|
CHEK2
|
checkpoint kinase 2
|
2.3573
|
|
TTC38
|
tetratricopeptide repeat domain 38
|
2.28078
|
|
PLAAT3
|
phospholipase A and acyltransferase 3
|
2.2193
|
|
CNOT7
|
CCR4-NOT transcription complex, subunit 7
|
2.15863
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.13574
|
|
CTSL
|
cathepsin L
|
2.12025
|
|
CAMK1
|
calcium/calmodulin-dependent protein kinase I
|
2.11221
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.10105
|
|
VGLL4
|
vestigial-like family member 4
|
2.08938
|
|
MTTP
|
microsomal triglyceride transfer protein
|
2.03634
|
|
SAV1
|
salvador family WW domain containing protein 1
|
2.01778
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-8.21694
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.75743
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.6288
|
|
LDHD
|
lactate dehydrogenase D
|
-4.50604
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.32124
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.28311
|
|
GNAS
|
GNAS complex locus
|
-3.93595
|
|
RPS5
|
ribosomal protein S5
|
-3.91047
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.74868
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.303
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.29345
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.20242
|
|
CCNB2
|
cyclin B2
|
-2.89133
|
|
EGF
|
epidermal growth factor
|
-2.78785
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.76564
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.74028
|
|
CCNB1
|
cyclin B1
|
-2.69173
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-2.36284
|
|
DRC4
|
dynein regulatory complex subunit 4
|
-2.28524
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.28276
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.26777
|
|
RPS29
|
ribosomal protein S29
|
-2.17592
|
|
REM1
|
RAS (RAD and GEM)-like GTP-binding 1
|
-2.17304
|
|
FN1
|
fibronectin 1
|
-2.05953
|
|
KRT4
|
keratin 4, type II
|
-2.04416
|
|
RPL18
|
ribosomal protein L18
|
-2.04135
|
|
KLHL29
|
kelch-like family member 29
|
-2.00675
|
