CRCGN013_HEPG2_24H:P17 Gene Set
Genes
31 genes differentially expressed following the CRCGN013_HEPG2_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.27127
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.53626
|
|
LCN2
|
lipocalin 2
|
4.50839
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.68206
|
|
HEBP1
|
heme binding protein 1
|
3.55925
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.39521
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.16998
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.0217
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.01349
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.94667
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.88358
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.84883
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.52903
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.47996
|
|
GPATCH8
|
G patch domain containing 8
|
2.38648
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.2862
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.21721
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.18808
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.70146
|
|
ZNF586
|
zinc finger protein 586
|
-4.5827
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.49663
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.41742
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.41101
|
|
LDHD
|
lactate dehydrogenase D
|
-3.34499
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.23479
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.99227
|
|
SNX11
|
sorting nexin 11
|
-2.89538
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.71632
|
|
EDN1
|
endothelin 1
|
-2.49321
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.1018
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.08628
|
