CRCGN013_HEPG2_24H:P19 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.25306
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.75748
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.47535
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.20544
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.00683
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.96376
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.87886
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.77515
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.70439
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.50053
|
|
EPHA3
|
EPH receptor A3
|
3.36688
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.07234
|
|
GPATCH8
|
G patch domain containing 8
|
2.76241
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.68793
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.56994
|
|
KEAP1
|
kelch-like ECH-associated protein 1
|
2.53588
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.2553
|
|
NUP133
|
nucleoporin 133kDa
|
2.2466
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.20611
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.40306
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-6.28649
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.6878
|
|
RAI14
|
retinoic acid induced 14
|
-4.387
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.25429
|
|
GNAS
|
GNAS complex locus
|
-4.19107
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.63816
|
|
SCAND1
|
SCAN domain containing 1
|
-3.29614
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.27705
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.26565
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.21428
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.05439
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.96579
|
|
RPS5
|
ribosomal protein S5
|
-2.90319
|
|
CCNB2
|
cyclin B2
|
-2.64947
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.53952
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.49032
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.45587
|
|
VAT1
|
vesicle amine transport 1
|
-2.44886
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.29092
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.20084
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.19075
|
|
MAP7
|
microtubule-associated protein 7
|
-2.1497
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.14527
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.12878
|
|
TLR4
|
toll-like receptor 4
|
-2.09705
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.08019
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.03008
|
