| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dinitrotoluene 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN013_HEPG2_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 7.31433 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.54018 |
| LOC122526780 | uncharacterized LOC122526780 | 4.91874 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.58049 |
| EPHA3 | EPH receptor A3 | 4.33441 |
| PLS1 | plastin 1 | 4.24319 |
| E2F2 | E2F transcription factor 2 | 4.19009 |
| EVL | Enah/Vasp-like | 4.10256 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.96496 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.9404 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.93076 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.91676 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 3.79988 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.5781 |
| ADRB2 | adrenoceptor beta 2, surface | 3.48085 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.47217 |
| TBP | TATA box binding protein | 3.41889 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.31889 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.2585 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.20793 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.90701 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.7912 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.64003 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.60563 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | 2.57184 |
| CCNF | cyclin F | 2.4701 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 2.46161 |
| CHEK2 | checkpoint kinase 2 | 2.38455 |
| SIRT3 | sirtuin 3 | 2.28836 |
| GRM2 | glutamate receptor, metabotropic 2 | 2.26422 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.26188 |
| SYN1 | synapsin I | 2.25192 |
| VGLL4 | vestigial-like family member 4 | 2.23856 |
| SATB1 | SATB homeobox 1 | 2.18495 |
| RERGL | RERG/RAS-like | 2.14475 |
| DLX6 | distal-less homeobox 6 | 2.09241 |
| HHAT | hedgehog acyltransferase | 2.04407 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 2.00367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.78294 |
| RAI14 | retinoic acid induced 14 | -4.67048 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.55015 |
| PCNA | proliferating cell nuclear antigen | -4.54723 |
| CCNB2 | cyclin B2 | -4.36054 |
| CCNB1 | cyclin B1 | -3.97318 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.89063 |
| COG7 | component of oligomeric golgi complex 7 | -3.83958 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.61457 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.27235 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -3.20501 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.17866 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.07979 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -2.96186 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.83306 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.67959 |
| TRAP1 | TNF receptor-associated protein 1 | -2.59423 |
| MAP7 | microtubule-associated protein 7 | -2.51796 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.49832 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.43684 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.40704 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.39002 |
| CTSD | cathepsin D | -2.38113 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.21904 |
| GRB7 | growth factor receptor-bound protein 7 | -2.19043 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.17739 |
| TOR1A | torsin family 1, member A (torsin A) | -2.09255 |
| HOMER3 | homer scaffolding protein 3 | -2.06625 |
| ADAP2 | ArfGAP with dual PH domains 2 | -2.02719 |
| KLK8 | kallikrein-related peptidase 8 | -2.02569 |
