| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dinitrotoluene 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN013_HEPG2_24H:P21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 10.0 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 10.0 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 5.65764 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.90211 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.36514 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 3.97629 |
| NOTCH1 | notch 1 | 3.9568 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.85963 |
| MYLK | myosin light chain kinase | 3.71974 |
| CCNF | cyclin F | 3.40959 |
| TBP | TATA box binding protein | 3.0741 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.68921 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.59248 |
| MCM3 | minichromosome maintenance complex component 3 | 2.55126 |
| HMOX1 | heme oxygenase 1 | 2.29266 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 2.22737 |
| BIRC3 | baculoviral IAP repeat containing 3 | 2.20592 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.18371 |
| NOSIP | nitric oxide synthase interacting protein | 2.18082 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.17517 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.15671 |
| NUP133 | nucleoporin 133kDa | 2.14434 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.08513 |
| SULF1 | sulfatase 1 | 2.07625 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 2.06769 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 2.05807 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | 2.00174 |
| ENOPH1 | enolase-phosphatase 1 | 2.00014 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.58012 |
| PCNA | proliferating cell nuclear antigen | -6.37759 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.74045 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.75061 |
| CD320 | CD320 molecule | -4.54037 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.14808 |
| TRIB3 | tribbles pseudokinase 3 | -3.70403 |
| LDHD | lactate dehydrogenase D | -3.66976 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.44883 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.35068 |
| TLCD3A | TLC domain containing 3A | -3.34661 |
| GDF15 | growth differentiation factor 15 | -3.29445 |
| CCNB1 | cyclin B1 | -3.21986 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.05472 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.76886 |
| RPL10A | ribosomal protein L10a | -2.35224 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.34215 |
| MXRA7 | matrix-remodelling associated 7 | -2.27921 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | -2.26995 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | -2.16516 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 | -2.11179 |
| VDAC1 | voltage-dependent anion channel 1 | -2.10831 |
| UBC | ubiquitin C | -2.10805 |
| ZNF133 | zinc finger protein 133 | -2.08767 |
| SLBP | stem-loop binding protein | -2.06125 |
| LGI1 | leucine-rich, glioma inactivated 1 | -2.01273 |
