CRCGN013_HEPG2_24H:P22 Gene Set
Genes
40 genes differentially expressed following the CRCGN013_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
6.17869
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.41584
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.02167
|
|
CHN1
|
chimerin 1
|
3.84335
|
|
LCN2
|
lipocalin 2
|
3.73733
|
|
RPL39L
|
ribosomal protein L39-like
|
3.71546
|
|
MYLK
|
myosin light chain kinase
|
3.6429
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.55347
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.39975
|
|
FRS2
|
fibroblast growth factor receptor substrate 2
|
3.15688
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.13383
|
|
HOXA10
|
homeobox A10
|
3.03339
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.62425
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.62018
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.52131
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.30842
|
|
CYCS
|
cytochrome c, somatic
|
2.19335
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.0992
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.04575
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.00647
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.84299
|
|
LDHD
|
lactate dehydrogenase D
|
-7.08984
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-5.02001
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.77914
|
|
CCNB2
|
cyclin B2
|
-4.07121
|
|
CD320
|
CD320 molecule
|
-3.53777
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.47038
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.97654
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.94612
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.86841
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.84546
|
|
GNAS
|
GNAS complex locus
|
-2.5533
|
|
DCK
|
deoxycytidine kinase
|
-2.52704
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.52623
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.44353
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.32709
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.32064
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.27535
|
|
EDN1
|
endothelin 1
|
-2.06283
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.04343
|
