| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN014_HEPG2_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS3 | integrator complex subunit 3 | 7.07694 |
| E2F2 | E2F transcription factor 2 | 6.6682 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.51234 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.59754 |
| ADRB2 | adrenoceptor beta 2, surface | 3.84957 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.76907 |
| PRR15L | proline rich 15-like | 3.20312 |
| MTERF3 | mitochondrial transcription termination factor 3 | 3.18697 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.14333 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.12821 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.11488 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 3.04011 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.83119 |
| ATP11B | ATPase, class VI, type 11B | 2.79615 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.77179 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.58722 |
| LOC122526780 | uncharacterized LOC122526780 | 2.56405 |
| SFTPB | surfactant protein B | 2.46291 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.43317 |
| LCN2 | lipocalin 2 | 2.41854 |
| EPHB2 | EPH receptor B2 | 2.38709 |
| MAP7 | microtubule-associated protein 7 | 2.31545 |
| BLMH | bleomycin hydrolase | 2.18802 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 2.18112 |
| STK25 | serine/threonine kinase 25 | 2.09423 |
| TMEM109 | transmembrane protein 109 | 2.09162 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.0685 |
| PRKCH | protein kinase C, eta | 2.04504 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 2.04375 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.00926 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.00449 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.76541 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.89005 |
| PCNA | proliferating cell nuclear antigen | -5.02544 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.31479 |
| TLR4 | toll-like receptor 4 | -4.24754 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.10732 |
| TLCD3A | TLC domain containing 3A | -4.08611 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.84377 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.74911 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -3.68908 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.62233 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.5618 |
| ADI1 | acireductone dioxygenase 1 | -3.40727 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.28824 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.83696 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.7775 |
| HMG20B | high mobility group 20B | -2.6448 |
| ZNF586 | zinc finger protein 586 | -2.59849 |
| CNPY4 | canopy FGF signaling regulator 4 | -2.42889 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.24695 |
| MMP8 | matrix metallopeptidase 8 | -2.22118 |
| EGF | epidermal growth factor | -2.21529 |
| RNF167 | ring finger protein 167 | -2.19391 |
| GRB7 | growth factor receptor-bound protein 7 | -2.15829 |
| CCNH | cyclin H | -2.09217 |
| PGLYRP1 | peptidoglycan recognition protein 1 | -2.08682 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.0608 |
| DUSP14 | dual specificity phosphatase 14 | -2.03003 |
| CHAMP1 | chromosome alignment maintaining phosphoprotein 1 | -2.01986 |
| DEFA4 | defensin, alpha 4, corticostatin | -2.0062 |
