CRCGN014_HEPG2_24H:A07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,4,5-trichlorophenoxyacetic acid 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

590 genes differentially expressed following the CRCGN014_HEPG2_24H:A07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADRB2 adrenoceptor beta 2, surface 9.39188
PPARG peroxisome proliferator-activated receptor gamma 8.75965
MAP7 microtubule-associated protein 7 7.4812
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 7.38795
UBQLN2 ubiquilin 2 7.09824
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 6.15631
CHMP6 charged multivesicular body protein 6 5.98871
TIAM1 T-cell lymphoma invasion and metastasis 1 5.86106
EPN2 epsin 2 5.73906
EPHB2 EPH receptor B2 5.20799
GATA3 GATA binding protein 3 5.03874
ABHD6 abhydrolase domain containing 6 4.97673
DYNLT3 dynein, light chain, Tctex-type 3 4.79586
LAGE3 L antigen family, member 3 4.39201
GSTZ1 glutathione S-transferase zeta 1 4.38556
HLA-DMA major histocompatibility complex, class II, DM alpha 4.35279
SYNGR3 synaptogyrin 3 4.06358
SNAP25 synaptosomal-associated protein, 25kDa 3.98776
MYLK myosin light chain kinase 3.88416
CXCL2 chemokine (C-X-C motif) ligand 2 3.79185
NOTCH1 notch 1 3.76612
PNKP polynucleotide kinase 3'-phosphatase 3.7586
ZNF589 zinc finger protein 589 3.75064
RPL39L ribosomal protein L39-like 3.67657
EGF epidermal growth factor 3.58801
SYNE2 spectrin repeat containing, nuclear envelope 2 3.57244
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.54815
AMDHD2 amidohydrolase domain containing 2 3.54545
HDGFL3 HDGF like 3 3.50956
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 3.47854
CCDC92 coiled-coil domain containing 92 3.47391
CHN1 chimerin 1 3.4696
C2CD2 C2 calcium-dependent domain containing 2 3.45756
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.45667
CSK c-src tyrosine kinase 3.3739
CIAO3 cytosolic iron-sulfur assembly component 3 3.33779
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.3136
CELA2B chymotrypsin-like elastase family, member 2B 3.26985
SMIM40 small integral membrane protein 40 3.26854
GPER1 G protein-coupled estrogen receptor 1 3.26571
TM2D3 TM2 domain containing 3 3.24577
MAMLD1 mastermind-like domain containing 1 3.2437
CRTAP cartilage associated protein 3.23864
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.22965
PLCD1 phospholipase C, delta 1 3.22445
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.20487
RBMS3 RNA binding motif, single stranded interacting protein 3 3.193
CCL2 chemokine (C-C motif) ligand 2 3.17883
MCOLN1 mucolipin 1 3.14456
RPP38 ribonuclease P/MRP 38kDa subunit 3.11752
PFKL phosphofructokinase, liver 3.09683
AMHR2 anti-Mullerian hormone receptor, type II 3.07684
E2F2 E2F transcription factor 2 3.03905
KCTD11 potassium channel tetramerization domain containing 11 3.0125
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.96737
ADGRE5 adhesion G protein-coupled receptor E5 2.94585
SOCS2 suppressor of cytokine signaling 2 2.9219
VAV3 vav 3 guanine nucleotide exchange factor 2.91871
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.9039
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.8873
PLS1 plastin 1 2.88597
MCHR1 melanin-concentrating hormone receptor 1 2.82278
FSCN2 fascin actin-bundling protein 2, retinal 2.81388
PRSS2 protease, serine, 2 (trypsin 2) 2.80595
ULBP2 UL16 binding protein 2 2.80566
SHH sonic hedgehog 2.80219
SOX21 SRY (sex determining region Y)-box 21 2.79561
COL5A3 collagen, type V, alpha 3 2.77034
WDR4 WD repeat domain 4 2.76884
CER1 cerberus 1, DAN family BMP antagonist 2.76841
FANCC Fanconi anemia, complementation group C 2.76473
MYO19 myosin XIX 2.76114
COL9A1 collagen, type IX, alpha 1 2.75512
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.75088
APLNR apelin receptor 2.75052
SSX5 synovial sarcoma, X breakpoint 5 2.74726
VGLL4 vestigial-like family member 4 2.73004
ZNF365 zinc finger protein 365 2.72457
KANK3 KN motif and ankyrin repeat domains 3 2.71515
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7 2.7081
ALK anaplastic lymphoma receptor tyrosine kinase 2.69647
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.69173
CTSZ cathepsin Z 2.69022
CUZD1 CUB and zona pellucida-like domains 1 2.6888
PEX11A peroxisomal biogenesis factor 11 alpha 2.68634
CAPN5 calpain 5 2.68187
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) 2.67967
INS insulin 2.67443
CHAD chondroadherin 2.67328
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.66925
TRPS1 trichorhinophalangeal syndrome I 2.66445
PAX1 paired box 1 2.65456
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.64887
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.63895
NTN1 netrin 1 2.63643
INSL6 insulin-like 6 2.63376
CLDN14 claudin 14 2.61197
SPATA17 spermatogenesis associated 17 2.61048
ADM2 adrenomedullin 2 2.58515
CELA3B chymotrypsin-like elastase family, member 3B 2.58495
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.58287
FAM107A family with sequence similarity 107, member A 2.57956
MAP3K6 mitogen-activated protein kinase kinase kinase 6 2.57891
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.57505
BARX2 BARX homeobox 2 2.56639
CELA2A chymotrypsin-like elastase family, member 2A 2.55987
PGPEP1 pyroglutamyl-peptidase I 2.55958
IRF5 interferon regulatory factor 5 2.55843
LGI2 leucine-rich repeat LGI family, member 2 2.55722
NRG2 neuregulin 2 2.55415
CDX1 caudal type homeobox 1 2.55247
CTRL chymotrypsin-like 2.55063
PNLIPRP1 pancreatic lipase-related protein 1 2.54981
CDON cell adhesion associated, oncogene regulated 2.54444
TSPO2 translocator protein 2 2.54402
HOXC8 homeobox C8 2.54305
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.5389
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.53619
ZBTB35 zinc finger and BTB domain containing 35 2.53616
H1-1 H1.1 linker histone, cluster member 2.5306
FN3K fructosamine 3 kinase 2.51584
RAMP3 receptor (G protein-coupled) activity modifying protein 3 2.50651
GLCE glucuronic acid epimerase 2.49587
AIRE autoimmune regulator 2.49367
PDE11A phosphodiesterase 11A 2.49008
CHAF1B chromatin assembly factor 1, subunit B (p60) 2.48434
HOXB9 homeobox B9 2.47951
APOLD1 apolipoprotein L domain containing 1 2.47627
CD40 CD40 molecule, TNF receptor superfamily member 5 2.47539
MTA2 metastasis associated 1 family, member 2 2.4726
EBF2 early B-cell factor 2 2.46835
SIRPG signal-regulatory protein gamma 2.46729
MEF2B myocyte enhancer factor 2B 2.46182
BLMH bleomycin hydrolase 2.45809
PRAMEF26 PRAME family member 26 2.45224
MMP3 matrix metallopeptidase 3 2.45141
EFNA4 ephrin-A4 2.44914
ADAM11 ADAM metallopeptidase domain 11 2.44884
GRPR gastrin-releasing peptide receptor 2.44676
PNLIP pancreatic lipase 2.43715
TTC28 tetratricopeptide repeat domain 28 2.43094
GPR173 G protein-coupled receptor 173 2.41866
DIPK2B divergent protein kinase domain 2B 2.41401
SLC75A1 solute carrier family 75 member 1 2.41365
APOL5 apolipoprotein L, 5 2.4134
CCL1 chemokine (C-C motif) ligand 1 2.41219
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.40783
LRRC36 leucine rich repeat containing 36 2.40656
RGS7 regulator of G-protein signaling 7 2.4051
DSG3 desmoglein 3 2.39813
GDF5 growth differentiation factor 5 2.39484
PRSS58 protease, serine, 58 2.3926
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 2.39043
SIRT6 sirtuin 6 2.39018
THBS4 thrombospondin 4 2.38777
TMEM74B transmembrane protein 74B 2.38684
MAST2 microtubule associated serine/threonine kinase 2 2.38635
HROB homologous recombination factor with OB-fold 2.38494
CCKAR cholecystokinin A receptor 2.37854
TP73 tumor protein p73 2.37778
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 2.37348
KLF7 Kruppel-like factor 7 (ubiquitous) 2.36343
FAM163A family with sequence similarity 163, member A 2.36293
CPA1 carboxypeptidase A1 (pancreatic) 2.36115
CPA2 carboxypeptidase A2 (pancreatic) 2.36074
TMEM168 transmembrane protein 168 2.35855
ADPRH ADP-ribosylarginine hydrolase 2.35703
CAMK1G calcium/calmodulin-dependent protein kinase IG 2.35609
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.35369
IL22 interleukin 22 2.35243
AARSD1 alanyl-tRNA synthetase domain containing 1 2.35072
TMEM176A transmembrane protein 176A 2.34958
NPY4R2 neuropeptide Y receptor Y4-2 2.34791
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled 2.34743
GAP43 growth associated protein 43 2.34682
CNGA1 cyclic nucleotide gated channel alpha 1 2.3396
ACSL6 acyl-CoA synthetase long-chain family member 6 2.33843
HDAC11 histone deacetylase 11 2.33634
IP6K2 inositol hexakisphosphate kinase 2 2.33386
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.33338
FSHR follicle stimulating hormone receptor 2.33007
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.32966
KRT36 keratin 36, type I 2.32637
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.32497
TEX28 testis expressed 28 2.32163
USP22 ubiquitin specific peptidase 22 2.31979
CYFIP2 cytoplasmic FMR1 interacting protein 2 2.31751
CHRM4 cholinergic receptor, muscarinic 4 2.31666
ALX4 ALX homeobox 4 2.31412
TRPA1 transient receptor potential cation channel, subfamily A, member 1 2.31282
PDLIM4 PDZ and LIM domain 4 2.306
TRAIP TRAF interacting protein 2.30584
TTC26 tetratricopeptide repeat domain 26 2.30565
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 2.30378
TMEM223 transmembrane protein 223 2.30257
KRT33A keratin 33A, type I 2.2987
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.29635
FAM53B family with sequence similarity 53, member B 2.29519
TLR6 toll-like receptor 6 2.29463
OMG oligodendrocyte myelin glycoprotein 2.29382
FBXO2 F-box protein 2 2.29325
CLCN6 chloride channel, voltage-sensitive 6 2.29265
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.2903
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.28592
HACL2 2-hydroxyacyl-CoA lyase 2 2.28508
DAPK2 death-associated protein kinase 2 2.28366
ADIRF adipogenesis regulatory factor 2.28185
NSG2 neuronal vesicle trafficking associated 2 2.28001
LAG3 lymphocyte-activation gene 3 2.27916
ETAA1 Ewing tumor-associated antigen 1 2.27583
PALS1 protein associated with LIN7 1, MAGUK p55 family member 2.27566
MST1R macrophage stimulating 1 receptor 2.27455
CABP5 calcium binding protein 5 2.27348
MTERF3 mitochondrial transcription termination factor 3 2.27335
WDR48 WD repeat domain 48 2.27242
SPRR2B small proline-rich protein 2B 2.26776
SPIN2B spindlin family, member 2B 2.26765
RCN3 reticulocalbin 3, EF-hand calcium binding domain 2.26755
DAO D-amino-acid oxidase 2.26664
ATF6B activating transcription factor 6 beta 2.26233
THSD7A thrombospondin, type I, domain containing 7A 2.26109
CASR calcium-sensing receptor 2.25908
SLC35F6 solute carrier family 35, member F6 2.25454
CLPS colipase, pancreatic 2.25285
MNMIP1 manchette microtubule inner protein 1 2.25254
SELENBP1 selenium binding protein 1 2.2507
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 2.24722
BAG1 BCL2-associated athanogene 2.24473
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 2.23909
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.23906
ADAM30 ADAM metallopeptidase domain 30 2.23425
CEP85 centrosomal protein 85kDa 2.23395
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.23251
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.23133
MAGEA1 melanoma antigen family A1 2.23076
CELA3A chymotrypsin-like elastase family, member 3A 2.23059
SIGLEC9 sialic acid binding Ig-like lectin 9 2.23011
B9D1 B9 protein domain 1 2.22588
RASL12 RAS-like, family 12 2.22572
PER1 period circadian clock 1 2.22509
BRD9 bromodomain containing 9 2.22109
DELE1 DAP3 binding cell death enhancer 1 2.2184
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.21814
SLC16A4 solute carrier family 16, member 4 2.2146
CDH4 cadherin 4, type 1, R-cadherin (retinal) 2.21338
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 2.21048
EXOC3 exocyst complex component 3 2.20955
IL11 interleukin 11 2.20671
SPATA31A3 SPATA31 subfamily A, member 3 2.20625
FAM114A1 family with sequence similarity 114, member A1 2.20564
MXRA8 matrix-remodelling associated 8 2.20564
CASKIN2 CASK interacting protein 2 2.20521
LCN1 lipocalin 1 2.20396
PHEX phosphate regulating endopeptidase homolog, X-linked 2.20334
SLC38A7 solute carrier family 38, member 7 2.20198
SSX3 synovial sarcoma, X breakpoint 3 2.20063
CD5 CD5 molecule 2.19817
INSL4 insulin-like 4 (placenta) 2.19506
TSPYL1 TSPY-like 1 2.19343
JADE2 jade family PHD finger 2 2.19308
MTG1 mitochondrial ribosome-associated GTPase 1 2.19213
LMTK1 lemur tail kinase 1 2.19033
ACADL acyl-CoA dehydrogenase, long chain 2.18962
BEGAIN brain-enriched guanylate kinase-associated 2.18904
GLRA2 glycine receptor, alpha 2 2.18883
SHOX short stature homeobox 2.18814
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 2.18562
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.1855
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 2.18313
WDR11 WD repeat domain 11 2.18063
BTNL2 butyrophilin-like 2 2.17795
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.17707
PCSK1 proprotein convertase subtilisin/kexin type 1 2.17505
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 2.17448
AQP6 aquaporin 6, kidney specific 2.17417
NEURL1 neuralized E3 ubiquitin protein ligase 1 2.17252
SOD3 superoxide dismutase 3, extracellular 2.17061
GLP2R glucagon-like peptide 2 receptor 2.16902
RNF123 ring finger protein 123 2.16675
LOC107985101 uncharacterized LOC107985101 2.16617
PNMA3 paraneoplastic Ma antigen 3 2.16488
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.16213
MRLN myoregulin 2.15852
REG3A regenerating islet-derived 3 alpha 2.15725
RGL4 ral guanine nucleotide dissociation stimulator-like 4 2.15712
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.15634
PCDHGA5 protocadherin gamma subfamily A, 5 2.15527
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.15465
POU3F3 POU class 3 homeobox 3 2.15429
PLA2G1B phospholipase A2, group IB (pancreas) 2.15015
HOXC5 homeobox C5 2.1491
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 2.14712
SUSD5 sushi domain containing 5 2.14632
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.14624
AQP4 aquaporin 4 2.14352
FXYD7 FXYD domain containing ion transport regulator 7 2.14274
TOB2 transducer of ERBB2, 2 2.14211
GRB10 growth factor receptor-bound protein 10 2.14143
SPRR1A small proline-rich protein 1A 2.14092
SIPA1L1 signal-induced proliferation-associated 1 like 1 2.13802
EPB41L3 erythrocyte membrane protein band 4.1-like 3 2.13724
ZSCAN2 zinc finger and SCAN domain containing 2 2.13607
MAPK7 mitogen-activated protein kinase 7 2.13565
PAQR5 progestin and adipoQ receptor family member V 2.13032
AQP1 aquaporin 1 (Colton blood group) 2.12955
WDR62 WD repeat domain 62 2.12829
CCN4 cellular communication network factor 4 2.12692
CDHR5 cadherin-related family member 5 2.12463
PEX12 peroxisomal biogenesis factor 12 2.12405
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.12323
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.12115
ONECUT2 one cut homeobox 2 2.12063
CA10 carbonic anhydrase X 2.12025
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.11973
SNED1 sushi, nidogen and EGF-like domains 1 2.11877
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.11846
ARHGAP19 Rho GTPase activating protein 19 2.11824
PEAK1 pseudopodium-enriched atypical kinase 1 2.11789
RGSL1 regulator of G-protein signaling like 1 2.11746
ZNF507 zinc finger protein 507 2.11734
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.11695
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 2.11658
FNDC3A fibronectin type III domain containing 3A 2.11596
GJA3 gap junction protein, alpha 3, 46kDa 2.11572
SPMAP2 sperm microtubule associated protein 2 2.11355
CHEK2 checkpoint kinase 2 2.11186
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.11086
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.11074
RAD54L2 RAD54-like 2 (S. cerevisiae) 2.10751
ACO1 aconitase 1, soluble 2.10509
TTC3 tetratricopeptide repeat domain 3 2.10443
OR7A17 olfactory receptor, family 7, subfamily A, member 17 2.10136
GP6 glycoprotein VI (platelet) 2.0997
RYR1 ryanodine receptor 1 (skeletal) 2.09843
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 2.09752
GOLIM4 golgi integral membrane protein 4 2.09642
PNLIPRP2 pancreatic lipase-related protein 2 2.09575
S100A3 S100 calcium binding protein A3 2.09462
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.08929
CBX2 chromobox homolog 2 2.0889
GFOD2 glucose-fructose oxidoreductase domain containing 2 2.08839
FBXO3 F-box protein 3 2.08803
KRT9 keratin 9, type I 2.08747
IQSEC3 IQ motif and Sec7 domain 3 2.08676
BCL3 B-cell CLL/lymphoma 3 2.08654
SPIB Spi-B transcription factor (Spi-1/PU.1 related) 2.08546
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.0853
YIPF2 Yip1 domain family, member 2 2.08303
TRAF1 TNF receptor-associated factor 1 2.08036
LMF2 lipase maturation factor 2 2.07987
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.07963
RASIP1 Ras interacting protein 1 2.07952
LTBP1 latent transforming growth factor beta binding protein 1 2.07921
LOC128966622 putative protein N-methyltransferase FAM86B2 2.07875
VPS50 VPS50 subunit of EARP/GARPII complex 2.07646
ECI2 enoyl-CoA delta isomerase 2 2.0759
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 2.07551
DGKQ diacylglycerol kinase, theta 110kDa 2.07341
ZC2HC1A zinc finger, C2HC-type containing 1A 2.07341
PHOX2A paired-like homeobox 2a 2.07207
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 2.06909
NKX2-5 NK2 homeobox 5 2.0687
ZBTB5 zinc finger and BTB domain containing 5 2.06869
PLD2 phospholipase D2 2.06765
OVOL1 ovo-like zinc finger 1 2.06497
SYN1 synapsin I 2.06195
LRRC3 leucine rich repeat containing 3 2.06187
ARB2A ARB2 cotranscriptional regulator A 2.06043
EDN2 endothelin 2 2.0603
ZNF302 zinc finger protein 302 2.05129
JPH3 junctophilin 3 2.05123
KCNIP2 Kv channel interacting protein 2 2.05087
WASF3 WAS protein family, member 3 2.04892
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.04825
PKLR pyruvate kinase, liver and RBC 2.048
TFDP3 transcription factor Dp family, member 3 2.04799
NPIPB6 nuclear pore complex interacting protein family, member B6 2.04793
SCN10A sodium channel, voltage gated, type X alpha subunit 2.04668
CCRL2 chemokine (C-C motif) receptor-like 2 2.0464
AURKC aurora kinase C 2.04544
COQ8B coenzyme Q8B 2.04522
PPCDC phosphopantothenoylcysteine decarboxylase 2.04505
TCIM transcriptional and immune response regulator 2.04195
ABLIM1 actin binding LIM protein 1 2.03996
ANGPTL7 angiopoietin-like 7 2.03957
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 2.03839
RUNDC3A RUN domain containing 3A 2.03824
TTC21B tetratricopeptide repeat domain 21B 2.0376
RXYLT1 ribitol xylosyltransferase 1 2.0342
LYPLA2 lysophospholipase II 2.03128
OSBPL7 oxysterol binding protein-like 7 2.03119
KIAA0232 KIAA0232 2.0307
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.0305
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 2.0299
RRAS related RAS viral (r-ras) oncogene homolog 2.02977
KRTAP5-3 keratin associated protein 5-3 2.02975
CLCN2 chloride channel, voltage-sensitive 2 2.02965
PSPN persephin 2.02914
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.02767
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 2.027
MFAP3 microfibrillar-associated protein 3 2.02607
CRHR2 corticotropin releasing hormone receptor 2 2.02397
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) 2.02381
HNF4G hepatocyte nuclear factor 4, gamma 2.02267
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 2.0225
GP2 glycoprotein 2 (zymogen granule membrane) 2.02183
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.01985
ACR acrosin 2.01932
LRRC49 leucine rich repeat containing 49 2.01906
SH2D3C SH2 domain containing 3C 2.01878
SDC2 syndecan 2 2.01862
PCDHGA3 protocadherin gamma subfamily A, 3 2.01803
GOLGA6B golgin A6 family, member B 2.01745
LIPC lipase, hepatic 2.0167
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.01643
TCN2 transcobalamin II 2.01565
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2.01306
PRKCE protein kinase C, epsilon 2.01293
FLOT2 flotillin 2 2.01253
ZFP91 ZFP91 zinc finger protein 2.00987
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.00974
AMH anti-Mullerian hormone 2.00773
WRAP53 WD repeat containing, antisense to TP53 2.00764
GPR17 G protein-coupled receptor 17 2.0064
AHI1 Abelson helper integration site 1 2.00624
WDR6 WD repeat domain 6 2.00609
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.00567
AFG3L2 AFG3-like AAA ATPase 2 2.00266

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.63956
KDM3A lysine (K)-specific demethylase 3A -7.46002
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -7.31853
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -7.13812
TRIB3 tribbles pseudokinase 3 -6.47906
GDF15 growth differentiation factor 15 -6.24949
CHMP4B charged multivesicular body protein 4B -6.23405
DNM1L dynamin 1-like -6.1056
CCNB1 cyclin B1 -6.00894
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.00506
ADI1 acireductone dioxygenase 1 -5.61962
PCNA proliferating cell nuclear antigen -5.59028
PEG10 paternally expressed 10 -5.16268
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -4.97561
TSPAN4 tetraspanin 4 -4.84289
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -4.47618
COG7 component of oligomeric golgi complex 7 -4.33049
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.32734
PUF60 poly-U binding splicing factor 60KDa -4.17968
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.08815
FAIM Fas apoptotic inhibitory molecule -4.03606
RFC2 replication factor C (activator 1) 2, 40kDa -3.94452
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.90244
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.83417
TUBB6 tubulin, beta 6 class V -3.75575
DUSP6 dual specificity phosphatase 6 -3.72207
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.62419
PCCB propionyl CoA carboxylase, beta polypeptide -3.60274
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -3.59783
MRPS2 mitochondrial ribosomal protein S2 -3.50341
ENOPH1 enolase-phosphatase 1 -3.47051
DSG2 desmoglein 2 -3.44948
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.42391
DERA deoxyribose-phosphate aldolase (putative) -3.41276
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -3.3844
CDC20 cell division cycle 20 -3.3724
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.26618
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.14535
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.14173
SEPHS2 selenophosphate synthetase 2 -3.13275
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -3.10228
CCDC86 coiled-coil domain containing 86 -3.05948
HMG20B high mobility group 20B -3.0402
CAB39 calcium binding protein 39 -3.02083
YME1L1 YME1-like 1 ATPase -3.01052
HEXB hexosaminidase B (beta polypeptide) -3.00697
SCAND1 SCAN domain containing 1 -2.98867
PTDSS2 phosphatidylserine synthase 2 -2.97092
ISOC1 isochorismatase domain containing 1 -2.94462
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.94128
PAK1IP1 PAK1 interacting protein 1 -2.89282
PTPRK protein tyrosine phosphatase, receptor type, K -2.82882
OSTM1 osteopetrosis associated transmembrane protein 1 -2.82569
ANXA4 annexin A4 -2.81074
EIF3I eukaryotic translation initiation factor 3, subunit I -2.7905
LYPLA1 lysophospholipase I -2.71618
THAP11 THAP domain containing 11 -2.71023
TRAPPC6A trafficking protein particle complex 6A -2.6626
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.63411
NUP42 nucleoporin 42 -2.62949
TES testin LIM domain protein -2.62518
CLEC11A C-type lectin domain family 11, member A -2.62095
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.59523
CCNB2 cyclin B2 -2.58195
RAB38 RAB38, member RAS oncogene family -2.57165
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -2.57068
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.56414
AKIP1 A kinase (PRKA) interacting protein 1 -2.55038
CUL1 cullin 1 -2.54023
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 -2.537
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.5338
SPAG4 sperm associated antigen 4 -2.52447
RIC8A RIC8 guanine nucleotide exchange factor A -2.52139
EPCAM epithelial cell adhesion molecule -2.50429
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -2.48982
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.47415
C2CD5 C2 calcium-dependent domain containing 5 -2.47232
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -2.46336
MNT MAX network transcriptional repressor -2.4405
THOP1 thimet oligopeptidase 1 -2.43262
KRT8 keratin 8, type II -2.43228
PPID peptidylprolyl isomerase D -2.42132
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 -2.40911
MEAF6 MYST/Esa1-associated factor 6 -2.40237
FLNA filamin A, alpha -2.39429
EMC8 ER membrane protein complex subunit 8 -2.38797
TRAPPC3 trafficking protein particle complex 3 -2.38513
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -2.38021
BFAR bifunctional apoptosis regulator -2.34965
ETV5 ets variant 5 -2.34084
TYR tyrosinase -2.336
MRPL23 mitochondrial ribosomal protein L23 -2.32961
SCRIB scribbled planar cell polarity protein -2.32052
ZC3H12A zinc finger CCCH-type containing 12A -2.31027
ZNF593 zinc finger protein 593 -2.30122
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 -2.29821
HPS5 Hermansky-Pudlak syndrome 5 -2.28111
CEP170B centrosomal protein 170B -2.27956
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.27604
LY6E lymphocyte antigen 6 complex, locus E -2.27177
SUMF2 sulfatase modifying factor 2 -2.26935
TIGAR TP53 induced glycolysis regulatory phosphatase -2.26895
HLA-E major histocompatibility complex, class I, E -2.25959
HTATSF1 HIV-1 Tat specific factor 1 -2.2569
CAPN3 calpain 3, (p94) -2.25572
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.2421
RBM34 RNA binding motif protein 34 -2.23801
COG2 component of oligomeric golgi complex 2 -2.23759
WDR12 WD repeat domain 12 -2.23708
MOSPD1 motile sperm domain containing 1 -2.22425
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -2.2182
EGLN1 egl-9 family hypoxia-inducible factor 1 -2.21818
GLRX2 glutaredoxin 2 -2.21805
RNF187 ring finger protein 187 -2.21603
GUSB glucuronidase, beta -2.21478
ADGRA2 adhesion G protein-coupled receptor A2 -2.19168
SPATS2 spermatogenesis associated, serine-rich 2 -2.18615
PPL periplakin -2.17659
CHEK1 checkpoint kinase 1 -2.16868
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.1648
HIRIP3 HIRA interacting protein 3 -2.16047
ATM ATM serine/threonine kinase -2.15545
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -2.14109
PLAAT4 phospholipase A and acyltransferase 4 -2.14029
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -2.13312
RBM15 RNA binding motif protein 15 -2.12783
RNF167 ring finger protein 167 -2.11791
TOR1A torsin family 1, member A (torsin A) -2.11757
CCL20 chemokine (C-C motif) ligand 20 -2.11646
TIMCC TIM double twin CX3C motif chaperone -2.11588
MRPS15 mitochondrial ribosomal protein S15 -2.11572
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -2.11223
MAGT1 magnesium transporter 1 -2.10909
DNAAF5 dynein, axonemal, assembly factor 5 -2.09733
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.09165
GSAP gamma-secretase activating protein -2.08718
MLANA melan-A -2.08687
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.07797
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.0745
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.07344
ZNF706 zinc finger protein 706 -2.0715
HOOK3 hook microtubule-tethering protein 3 -2.06533
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.06224
INSIG1 insulin induced gene 1 -2.05377
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14 -2.05204
GNAS GNAS complex locus -2.04981
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -2.04374
MORC2 MORC family CW-type zinc finger 2 -2.04175
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.03886
GNS glucosamine (N-acetyl)-6-sulfatase -2.03384
TRIM68 tripartite motif containing 68 -2.02829
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -2.02472
SH3GL1 SH3-domain GRB2-like 1 -2.02436
TTC13 tetratricopeptide repeat domain 13 -2.0216
ACTMAP actin maturation protease -2.02071
FOS FBJ murine osteosarcoma viral oncogene homolog -2.01465
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 -2.01304
APOE apolipoprotein E -2.01252
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -2.01107
INHBE inhibin, beta E -2.00964
HMOX2 heme oxygenase 2 -2.00887
GTF3A general transcription factor IIIA -2.00003