CRCGN014_HEPG2_24H:A09 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.05436
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
6.58151
|
|
PRR15L
|
proline rich 15-like
|
4.59434
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.30952
|
|
GPATCH8
|
G patch domain containing 8
|
4.0121
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.97278
|
|
CBR3
|
carbonyl reductase 3
|
3.89387
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.76636
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.41572
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.03465
|
|
EPHA3
|
EPH receptor A3
|
2.80243
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.67877
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
2.67199
|
|
GATA3
|
GATA binding protein 3
|
2.67168
|
|
UBQLN2
|
ubiquilin 2
|
2.66364
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.42213
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.36304
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.34323
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.28252
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.20895
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.10567
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.05665
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.05056
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.03452
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.69577
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.13549
|
|
SCAND1
|
SCAN domain containing 1
|
-3.88629
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.38064
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.14688
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.04281
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.96231
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.9078
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.75871
|
|
CCNB2
|
cyclin B2
|
-2.69878
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.66338
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.63154
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.54774
|
|
TLR4
|
toll-like receptor 4
|
-2.45764
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.37767
|
|
RAI14
|
retinoic acid induced 14
|
-2.34234
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.33933
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.30654
|
|
CDC20
|
cell division cycle 20
|
-2.23731
|
|
ADORA2B
|
adenosine A2b receptor
|
-2.1078
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.00254
|
