| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenylephrine 40.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN014_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.98942 |
| UBQLN2 | ubiquilin 2 | 5.24408 |
| STIMATE | STIM activating enhancer | 5.18164 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.52977 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.11246 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.93088 |
| MAP7 | microtubule-associated protein 7 | 3.72298 |
| ZNF589 | zinc finger protein 589 | 3.72295 |
| LAGE3 | L antigen family, member 3 | 3.67074 |
| EPHA3 | EPH receptor A3 | 3.36415 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.1945 |
| PMM2 | phosphomannomutase 2 | 2.96406 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.93571 |
| GATA2 | GATA binding protein 2 | 2.81015 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.80009 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.72765 |
| VGLL4 | vestigial-like family member 4 | 2.59788 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.50846 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 2.4259 |
| NRTN | neurturin | 2.42473 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 2.36157 |
| COPS7A | COP9 signalosome subunit 7A | 2.29555 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.28253 |
| TRAM2 | translocation associated membrane protein 2 | 2.25953 |
| RBBP7 | retinoblastoma binding protein 7 | 2.2387 |
| KLHL9 | kelch-like family member 9 | 2.23589 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.23202 |
| RRAGA | Ras-related GTP binding A | 2.11222 |
| ADPRH | ADP-ribosylarginine hydrolase | 2.08101 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic | 2.08026 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 2.00985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.0509 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.73122 |
| SCAND1 | SCAN domain containing 1 | -5.66648 |
| LAP3 | leucine aminopeptidase 3 | -4.63096 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.91565 |
| TWF2 | twinfilin actin binding protein 2 | -3.71023 |
| GOLT1B | golgi transport 1B | -3.40829 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.36756 |
| PEG10 | paternally expressed 10 | -3.26924 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.01295 |
| CCNB2 | cyclin B2 | -2.98933 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -2.96211 |
| PGM1 | phosphoglucomutase 1 | -2.91602 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.6687 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.56743 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.32902 |
| GIPC1 | GIPC PDZ domain containing family, member 1 | -2.28534 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.19266 |
| NMRK1 | nicotinamide riboside kinase 1 | -2.10048 |
| RBM34 | RNA binding motif protein 34 | -2.07858 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.07316 |
| RNF167 | ring finger protein 167 | -2.00413 |
