CRCGN014_HEPG2_24H:A13 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_24H:A13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.34955
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.56812
|
|
INTS3
|
integrator complex subunit 3
|
4.47267
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
3.61786
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.49519
|
|
IDE
|
insulin-degrading enzyme
|
3.25017
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.22567
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.11832
|
|
EGF
|
epidermal growth factor
|
3.10451
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.01766
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.97369
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.89422
|
|
MAP7
|
microtubule-associated protein 7
|
2.86781
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.85492
|
|
PFKL
|
phosphofructokinase, liver
|
2.83088
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.71653
|
|
PRR15L
|
proline rich 15-like
|
2.49788
|
|
SATB1
|
SATB homeobox 1
|
2.38058
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.31551
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.15678
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.10138
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.09899
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.43755
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.62814
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.79698
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.78261
|
|
CD320
|
CD320 molecule
|
-4.60656
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-4.09733
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.61348
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.39414
|
|
DNM1L
|
dynamin 1-like
|
-3.35383
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.02462
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.01456
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.00032
|
|
RBM34
|
RNA binding motif protein 34
|
-2.94627
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.88441
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.87303
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.81634
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.74753
|
|
LDHD
|
lactate dehydrogenase D
|
-2.52557
|
|
GNAS
|
GNAS complex locus
|
-2.42183
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.40127
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.24571
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.20336
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.04694
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.04616
|
