| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorpropamide 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN014_HEPG2_24H:A19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.50394 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.75109 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.33539 |
| CBR3 | carbonyl reductase 3 | 4.29984 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.27883 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.23419 |
| KLHL21 | kelch-like family member 21 | 4.02815 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.98671 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.95283 |
| IDE | insulin-degrading enzyme | 3.62264 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.60148 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.56945 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.4733 |
| E2F2 | E2F transcription factor 2 | 3.43456 |
| RRAGA | Ras-related GTP binding A | 3.33697 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.25449 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.79133 |
| RPS26 | ribosomal protein S26 | 2.56903 |
| HEBP1 | heme binding protein 1 | 2.54033 |
| NUP85 | nucleoporin 85kDa | 2.30846 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.27665 |
| ZNF589 | zinc finger protein 589 | 2.26292 |
| BAX | BCL2-associated X protein | 2.17671 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.17361 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 | 2.16719 |
| TRAM2 | translocation associated membrane protein 2 | 2.14355 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.13301 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 2.12384 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | 2.11936 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.01331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -8.7532 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.71956 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.56422 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.78916 |
| DNM1L | dynamin 1-like | -4.6336 |
| TRIB3 | tribbles pseudokinase 3 | -4.57835 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.29134 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.02615 |
| CDC20 | cell division cycle 20 | -3.83409 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.75477 |
| CCNB2 | cyclin B2 | -3.7449 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.67113 |
| YME1L1 | YME1-like 1 ATPase | -3.17884 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.02277 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.00683 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.76327 |
| CA4 | carbonic anhydrase IV | -2.68918 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.41033 |
| LYRM2 | LYR motif containing 2 | -2.38542 |
| OLFML2A | olfactomedin-like 2A | -2.31259 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | -2.29866 |
| LARP6 | La ribonucleoprotein domain family, member 6 | -2.12164 |
| CA2 | carbonic anhydrase II | -2.11677 |
| TRIM56 | tripartite motif containing 56 | -2.07206 |
| GNAS | GNAS complex locus | -2.05545 |
| COG7 | component of oligomeric golgi complex 7 | -2.04343 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -2.02535 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.02106 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.01798 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -2.01398 |
