| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hexachlorobenzene 2.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN014_HEPG2_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 5.43253 |
| MAMLD1 | mastermind-like domain containing 1 | 5.35695 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 5.1944 |
| E2F2 | E2F transcription factor 2 | 4.65875 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.6386 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.55355 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.38075 |
| SFTPB | surfactant protein B | 4.01768 |
| IDE | insulin-degrading enzyme | 4.00143 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 3.7299 |
| PRKCH | protein kinase C, eta | 3.57822 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | 3.3643 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.29557 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.18115 |
| EVL | Enah/Vasp-like | 2.92145 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 2.85535 |
| MAP7 | microtubule-associated protein 7 | 2.61548 |
| TBP | TATA box binding protein | 2.5834 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.56061 |
| KIF20A | kinesin family member 20A | 2.5042 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.49305 |
| CHN1 | chimerin 1 | 2.394 |
| TENT5C | terminal nucleotidyltransferase 5C | 2.3937 |
| MBNL3 | muscleblind-like splicing regulator 3 | 2.29155 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.27075 |
| KIF18B | kinesin family member 18B | 2.22255 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 2.19925 |
| APOA1 | apolipoprotein A-I | 2.1755 |
| LY75-CD302 | LY75-CD302 readthrough | 2.16545 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.1142 |
| JADE2 | jade family PHD finger 2 | 2.06785 |
| PODNL1 | podocan-like 1 | 2.0515 |
| ICAM1 | intercellular adhesion molecule 1 | 2.0415 |
| GOLPH3L | golgi phosphoprotein 3-like | 2.0175 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | 2.00325 |
| LHX3 | LIM homeobox 3 | 2.0016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| DSG2 | desmoglein 2 | -5.41415 |
| DNM1L | dynamin 1-like | -5.3963 |
| TSPAN4 | tetraspanin 4 | -5.04692 |
| ADI1 | acireductone dioxygenase 1 | -4.94845 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -4.9386 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.85505 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.6972 |
| CD320 | CD320 molecule | -4.66275 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.69165 |
| COG2 | component of oligomeric golgi complex 2 | -3.4431 |
| GDF15 | growth differentiation factor 15 | -3.2116 |
| TWF2 | twinfilin actin binding protein 2 | -3.12455 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.09595 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.9603 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.9529 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.81135 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.7421 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.66865 |
| EGF | epidermal growth factor | -2.6672 |
| CCNH | cyclin H | -2.5901 |
| WASHC4 | WASH complex subunit 4 | -2.49172 |
| HYOU1 | hypoxia up-regulated 1 | -2.4516 |
| ZNF12 | zinc finger protein 12 | -2.4137 |
| CDK5 | cyclin-dependent kinase 5 | -2.3908 |
| HSPA8 | heat shock 70kDa protein 8 | -2.30328 |
| PCNA | proliferating cell nuclear antigen | -2.2485 |
| PRPF4 | pre-mRNA processing factor 4 | -2.24222 |
| PPOX | protoporphyrinogen oxidase | -2.23635 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.20345 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -2.1333 |
| ATF5 | activating transcription factor 5 | -2.04737 |
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 | -2.0431 |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) | -2.02385 |
| CUX2 | cut-like homeobox 2 | -2.02155 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -2.00625 |
| MLF2 | myeloid leukemia factor 2 | -2.00175 |
