CRCGN014_HEPG2_24H:A23 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.95378
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.07357
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
4.53645
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.16718
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.16193
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.91392
|
|
NOTCH1
|
notch 1
|
3.79708
|
|
IDE
|
insulin-degrading enzyme
|
3.76971
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.70246
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
3.64319
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.50758
|
|
CDC25B
|
cell division cycle 25B
|
3.12831
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.06563
|
|
SFTPB
|
surfactant protein B
|
2.94309
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.8809
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.81158
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.6744
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.57438
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.39011
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.26499
|
|
MYCBP2
|
MYC binding protein 2, E3 ubiquitin protein ligase
|
2.11548
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.03939
|
|
H2BC12
|
H2B clustered histone 12
|
2.00769
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.37779
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.09426
|
|
SCAND1
|
SCAN domain containing 1
|
-3.90238
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.874
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.76701
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.68079
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.51881
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.85018
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.73965
|
|
FHL2
|
four and a half LIM domains 2
|
-2.64567
|
|
RNF167
|
ring finger protein 167
|
-2.59075
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.50132
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.47568
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.43744
|
|
PPP2R5A
|
protein phosphatase 2, regulatory subunit B', alpha
|
-2.42433
|
|
CCNB2
|
cyclin B2
|
-2.41214
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
-2.34921
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.30328
|
|
TLR4
|
toll-like receptor 4
|
-2.25503
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.25093
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.17384
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.03582
|
