| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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81 genes differentially expressed following the CRCGN014_HEPG2_24H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 6.71003 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 5.12756 |
| JADE2 | jade family PHD finger 2 | 5.10004 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.39346 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.34108 |
| MAP7 | microtubule-associated protein 7 | 4.30559 |
| MOK | MOK protein kinase | 4.11759 |
| ADRB2 | adrenoceptor beta 2, surface | 4.02623 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.66355 |
| EGF | epidermal growth factor | 3.48537 |
| MYLK | myosin light chain kinase | 3.48444 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.2036 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.13419 |
| MAMLD1 | mastermind-like domain containing 1 | 3.09166 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.95235 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.84693 |
| UBQLN2 | ubiquilin 2 | 2.82354 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.68925 |
| STAP2 | signal transducing adaptor family member 2 | 2.64923 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.63862 |
| LOC122526780 | uncharacterized LOC122526780 | 2.62148 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.56012 |
| UFM1 | ubiquitin-fold modifier 1 | 2.49934 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.48231 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.46883 |
| LCN2 | lipocalin 2 | 2.37539 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.35508 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.31583 |
| WASF3 | WAS protein family, member 3 | 2.29431 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.28581 |
| ABHD6 | abhydrolase domain containing 6 | 2.28421 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.26521 |
| CCDC92 | coiled-coil domain containing 92 | 2.26345 |
| CHN1 | chimerin 1 | 2.23155 |
| CCNF | cyclin F | 2.18477 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase | 2.15526 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.09197 |
| SLC75A1 | solute carrier family 75 member 1 | 2.06748 |
| GFRA1 | GDNF family receptor alpha 1 | 2.0658 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.02873 |
| SPIN2B | spindlin family, member 2B | 2.01181 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -6.41758 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.18462 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.75436 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.73711 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.6105 |
| TLCD3A | TLC domain containing 3A | -3.50212 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.45219 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -3.30102 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.17364 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.13567 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.09971 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.08079 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.0696 |
| FASTKD5 | FAST kinase domains 5 | -3.0347 |
| LAP3 | leucine aminopeptidase 3 | -3.01498 |
| CDC20 | cell division cycle 20 | -2.98863 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.8792 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.84558 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -2.75523 |
| NCK1 | NCK adaptor protein 1 | -2.74031 |
| PCNA | proliferating cell nuclear antigen | -2.71262 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.68949 |
| RBM34 | RNA binding motif protein 34 | -2.62307 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.57364 |
| DSG2 | desmoglein 2 | -2.55133 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.51669 |
| LDHD | lactate dehydrogenase D | -2.49834 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.48182 |
| CCDC86 | coiled-coil domain containing 86 | -2.42837 |
| TMEM204 | transmembrane protein 204 | -2.39504 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.2351 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.22849 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.21205 |
| NGRN | neugrin, neurite outgrowth associated | -2.19087 |
| TRIB3 | tribbles pseudokinase 3 | -2.12723 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.11343 |
| GOLT1B | golgi transport 1B | -2.06551 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.05973 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.05462 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.05086 |
