| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dl-menthol 41.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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70 genes differentially expressed following the CRCGN014_HEPG2_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 8.17371 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.90566 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.35579 |
| CHMP6 | charged multivesicular body protein 6 | 5.34026 |
| CHN1 | chimerin 1 | 4.38178 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 3.11389 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.00806 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.9321 |
| DIPK1A | divergent protein kinase domain 1A | 2.65562 |
| GRB10 | growth factor receptor-bound protein 10 | 2.58506 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.57641 |
| RB1 | retinoblastoma 1 | 2.57244 |
| CDC45 | cell division cycle 45 | 2.52972 |
| SFTPB | surfactant protein B | 2.40293 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 | 2.33054 |
| ATP11B | ATPase, class VI, type 11B | 2.32107 |
| ICAM1 | intercellular adhesion molecule 1 | 2.3179 |
| C8A | complement component 8, alpha polypeptide | 2.30615 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 2.28996 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.27734 |
| KIF20A | kinesin family member 20A | 2.25334 |
| MYOD1 | myogenic differentiation 1 | 2.24463 |
| CEP57 | centrosomal protein 57kDa | 2.15226 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 2.09523 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.09389 |
| PRSS53 | protease, serine, 53 | 2.07701 |
| NAXD | NAD(P)HX dehydratase | 2.07401 |
| RDH16 | retinol dehydrogenase 16 (all-trans) | 2.07176 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.05917 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 2.04114 |
| LIMD2 | LIM domain containing 2 | 2.03105 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 2.01696 |
| WDR62 | WD repeat domain 62 | 2.00812 |
| DNA2 | DNA replication helicase/nuclease 2 | 2.00626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.14944 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.8401 |
| LAP3 | leucine aminopeptidase 3 | -5.46652 |
| CDC20 | cell division cycle 20 | -5.37836 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.32427 |
| LDHD | lactate dehydrogenase D | -4.94962 |
| VAT1 | vesicle amine transport 1 | -4.92799 |
| SCAND1 | SCAN domain containing 1 | -4.58829 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.47425 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.4345 |
| CCDC86 | coiled-coil domain containing 86 | -4.31162 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -4.28238 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.62566 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -3.42888 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.42885 |
| RGS2 | regulator of G-protein signaling 2 | -3.32426 |
| HMG20B | high mobility group 20B | -3.24371 |
| TLCD3A | TLC domain containing 3A | -3.24249 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.23162 |
| LYPLA1 | lysophospholipase I | -2.90194 |
| MRPL15 | mitochondrial ribosomal protein L15 | -2.63522 |
| LBHD1 | LBH domain containing 1 | -2.50032 |
| VDAC1 | voltage-dependent anion channel 1 | -2.25264 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -2.22361 |
| PAK1IP1 | PAK1 interacting protein 1 | -2.21356 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -2.1921 |
| C1QL1 | complement component 1, q subcomponent-like 1 | -2.16066 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -2.14424 |
| RBM34 | RNA binding motif protein 34 | -2.12206 |
| GPN1 | GPN-loop GTPase 1 | -2.1214 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -2.05956 |
| ADRM1 | adhesion regulating molecule 1 | -2.05182 |
| NMI | N-myc (and STAT) interactor | -2.04293 |
| CTSD | cathepsin D | -2.01725 |
| ACOD1 | aconitate decarboxylase 1 | -2.0056 |
| CDCP1 | CUB domain containing protein 1 | -2.0048 |