CRCGN014_HEPG2_24H:B05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dl-menthol 41.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

70 genes differentially expressed following the CRCGN014_HEPG2_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 8.17371
GSTZ1 glutathione S-transferase zeta 1 5.90566
BACE2 beta-site APP-cleaving enzyme 2 5.35579
CHMP6 charged multivesicular body protein 6 5.34026
CHN1 chimerin 1 4.38178
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 3.11389
CDPF1 cysteine-rich, DPF motif domain containing 1 3.00806
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.9321
DIPK1A divergent protein kinase domain 1A 2.65562
GRB10 growth factor receptor-bound protein 10 2.58506
CD40 CD40 molecule, TNF receptor superfamily member 5 2.57641
RB1 retinoblastoma 1 2.57244
CDC45 cell division cycle 45 2.52972
SFTPB surfactant protein B 2.40293
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.33054
ATP11B ATPase, class VI, type 11B 2.32107
ICAM1 intercellular adhesion molecule 1 2.3179
C8A complement component 8, alpha polypeptide 2.30615
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 2.28996
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.27734
KIF20A kinesin family member 20A 2.25334
MYOD1 myogenic differentiation 1 2.24463
CEP57 centrosomal protein 57kDa 2.15226
CXCL6 chemokine (C-X-C motif) ligand 6 2.09523
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.09389
PRSS53 protease, serine, 53 2.07701
NAXD NAD(P)HX dehydratase 2.07401
RDH16 retinol dehydrogenase 16 (all-trans) 2.07176
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.05917
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.04114
LIMD2 LIM domain containing 2 2.03105
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.01696
WDR62 WD repeat domain 62 2.00812
DNA2 DNA replication helicase/nuclease 2 2.00626

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -6.14944
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.8401
LAP3 leucine aminopeptidase 3 -5.46652
CDC20 cell division cycle 20 -5.37836
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.32427
LDHD lactate dehydrogenase D -4.94962
VAT1 vesicle amine transport 1 -4.92799
SCAND1 SCAN domain containing 1 -4.58829
FABP5 fatty acid binding protein 5 (psoriasis-associated) -4.47425
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.4345
CCDC86 coiled-coil domain containing 86 -4.31162
ITGB1BP1 integrin beta 1 binding protein 1 -4.28238
DERA deoxyribose-phosphate aldolase (putative) -3.62566
RALB v-ral simian leukemia viral oncogene homolog B -3.42888
LOC124907782 dual specificity protein phosphatase 22 -3.42885
RGS2 regulator of G-protein signaling 2 -3.32426
HMG20B high mobility group 20B -3.24371
TLCD3A TLC domain containing 3A -3.24249
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.23162
LYPLA1 lysophospholipase I -2.90194
MRPL15 mitochondrial ribosomal protein L15 -2.63522
LBHD1 LBH domain containing 1 -2.50032
VDAC1 voltage-dependent anion channel 1 -2.25264
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.22361
PAK1IP1 PAK1 interacting protein 1 -2.21356
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -2.1921
C1QL1 complement component 1, q subcomponent-like 1 -2.16066
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.14424
RBM34 RNA binding motif protein 34 -2.12206
GPN1 GPN-loop GTPase 1 -2.1214
SPATS2 spermatogenesis associated, serine-rich 2 -2.05956
ADRM1 adhesion regulating molecule 1 -2.05182
NMI N-myc (and STAT) interactor -2.04293
CTSD cathepsin D -2.01725
ACOD1 aconitate decarboxylase 1 -2.0056
CDCP1 CUB domain containing protein 1 -2.0048