CRCGN014_HEPG2_24H:B09 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_24H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
8.7856
|
|
MAP7
|
microtubule-associated protein 7
|
7.18817
|
|
MYLK
|
myosin light chain kinase
|
5.37184
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.9309
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.86305
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.81261
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.20505
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.55794
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.48364
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.45178
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.44344
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
3.39233
|
|
IDE
|
insulin-degrading enzyme
|
3.32471
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.28378
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.86644
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.76662
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.53294
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.36723
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.28829
|
|
CHEK2
|
checkpoint kinase 2
|
2.27394
|
|
CHN1
|
chimerin 1
|
2.2625
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.1684
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.13674
|
|
TBPL1
|
TBP-like 1
|
2.09196
|
|
KLHDC2
|
kelch domain containing 2
|
2.04868
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.03217
|
|
NOTCH1
|
notch 1
|
2.0311
|
|
SFT2D2
|
SFT2 domain containing 2
|
2.00903
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-6.52058
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-5.3515
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.22052
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.18595
|
|
VAT1
|
vesicle amine transport 1
|
-5.13003
|
|
LDHD
|
lactate dehydrogenase D
|
-5.02235
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.00662
|
|
CAB39
|
calcium binding protein 39
|
-3.79696
|
|
CDC20
|
cell division cycle 20
|
-3.74694
|
|
PYCR1
|
pyrroline-5-carboxylate reductase 1
|
-3.58148
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.43335
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.31953
|
|
NVL
|
nuclear VCP-like
|
-2.7625
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.52787
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.40219
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.38392
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.23989
|
|
CCNB2
|
cyclin B2
|
-2.22305
|
|
ASB8
|
ankyrin repeat and SOCS box containing 8
|
-2.13216
|
