CRCGN014_HEPG2_24H:B10 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_24H:B10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.57
|
|
MAP7
|
microtubule-associated protein 7
|
4.18453
|
|
EVL
|
Enah/Vasp-like
|
4.18286
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.91149
|
|
INTS3
|
integrator complex subunit 3
|
3.78408
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.43096
|
|
GPATCH8
|
G patch domain containing 8
|
3.42728
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.42143
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.27402
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.27138
|
|
CBR3
|
carbonyl reductase 3
|
3.26733
|
|
E2F2
|
E2F transcription factor 2
|
3.09246
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
3.0023
|
|
CYCS
|
cytochrome c, somatic
|
2.96465
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.81069
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.74255
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.6478
|
|
CHN1
|
chimerin 1
|
2.56655
|
|
GATA3
|
GATA binding protein 3
|
2.53399
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.49901
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.39377
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.37857
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.26312
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.1987
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.18406
|
|
NAALAD2
|
N-acetylated alpha-linked acidic dipeptidase 2
|
2.1519
|
|
PRR15L
|
proline rich 15-like
|
2.09261
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.79524
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.0543
|
|
SCAND1
|
SCAN domain containing 1
|
-6.99526
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.44039
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.25005
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.65857
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.58174
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.52656
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.15736
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.10438
|
|
GOLT1B
|
golgi transport 1B
|
-3.04505
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.02409
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.79025
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.63958
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.44236
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.42768
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.38126
|
|
RAI14
|
retinoic acid induced 14
|
-2.31834
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.19942
|
|
HMG20B
|
high mobility group 20B
|
-2.03763
|
