CRCGN014_HEPG2_24H:B15 Gene Set
Genes
52 genes differentially expressed following the CRCGN014_HEPG2_24H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.08377
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.88925
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.53572
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.04437
|
|
INTS3
|
integrator complex subunit 3
|
3.92494
|
|
TATDN2
|
TatD DNase domain containing 2
|
3.15904
|
|
SFTPB
|
surfactant protein B
|
3.09841
|
|
PRKCH
|
protein kinase C, eta
|
3.0959
|
|
CBR3
|
carbonyl reductase 3
|
3.08824
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.05995
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.95881
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.79948
|
|
SIRT3
|
sirtuin 3
|
2.5153
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.4361
|
|
HEYL
|
hes-related family bHLH transcription factor with YRPW motif-like
|
2.31831
|
|
EEF1AKMT4-ECE2
|
EEF1AKMT4-ECE2 readthrough
|
2.26823
|
|
EYA3
|
EYA transcriptional coactivator and phosphatase 3
|
2.24084
|
|
SMAD9
|
SMAD family member 9
|
2.22766
|
|
POLD1
|
polymerase (DNA directed), delta 1, catalytic subunit
|
2.21786
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.21345
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.20317
|
|
STX1A
|
syntaxin 1A (brain)
|
2.1604
|
|
VGLL4
|
vestigial-like family member 4
|
2.13837
|
|
POMC
|
proopiomelanocortin
|
2.1306
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.10327
|
|
CALCB
|
calcitonin-related polypeptide beta
|
2.08431
|
|
CCNF
|
cyclin F
|
2.06285
|
|
DBF4B
|
DBF4 zinc finger B
|
2.05776
|
|
ZNF816
|
zinc finger protein 816
|
2.0546
|
|
KCNAB3
|
potassium channel, voltage gated subfamily A regulatory beta subunit 3
|
2.04856
|
|
DDX51
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
|
2.0374
|
|
TESK1
|
testis-specific kinase 1
|
2.03487
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.03369
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.48882
|
|
LDHD
|
lactate dehydrogenase D
|
-6.69942
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.31263
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.41934
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-3.15274
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.085
|
|
GNAS
|
GNAS complex locus
|
-3.06774
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.97316
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.79457
|
|
REEP5
|
receptor accessory protein 5
|
-2.71949
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.6009
|
|
RNF167
|
ring finger protein 167
|
-2.38255
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.35953
|
|
SLC20A1
|
solute carrier family 20 (phosphate transporter), member 1
|
-2.23957
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.20148
|
|
CDC25B
|
cell division cycle 25B
|
-2.14795
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.08543
|
|
CCNB2
|
cyclin B2
|
-2.04435
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.01446
|
