CRCGN014_HEPG2_24H:B17 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:B17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
7.19478
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
6.91944
|
|
E2F2
|
E2F transcription factor 2
|
4.67292
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.98214
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.93708
|
|
TBPL1
|
TBP-like 1
|
3.8188
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.73428
|
|
HOXA10
|
homeobox A10
|
3.42348
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.02403
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.99766
|
|
CYCS
|
cytochrome c, somatic
|
2.97934
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.86136
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.81709
|
|
NOTCH1
|
notch 1
|
2.73839
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.72906
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.70186
|
|
UBQLN2
|
ubiquilin 2
|
2.67024
|
|
STK10
|
serine/threonine kinase 10
|
2.34104
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.28592
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.18794
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.12363
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.1075
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.04732
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.00261
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.07674
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.25787
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.84599
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.82449
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.80088
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.66895
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.57132
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.19887
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-3.05171
|
|
LDHD
|
lactate dehydrogenase D
|
-3.00247
|
|
CDC20
|
cell division cycle 20
|
-2.65459
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.62911
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.34168
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.31976
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.0498
|
|
HOXB3
|
homeobox B3
|
-2.02733
|
