| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | michler's ketone 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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94 genes differentially expressed following the CRCGN014_HEPG2_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.42071 |
| H2BC12 | H2B clustered histone 12 | 4.22785 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 4.18846 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.95269 |
| STK10 | serine/threonine kinase 10 | 3.92515 |
| SFTPB | surfactant protein B | 3.6152 |
| NOTCH1 | notch 1 | 3.6131 |
| SQOR | sulfide quinone oxidoreductase | 3.58521 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.24989 |
| BLCAP | bladder cancer associated protein | 3.17911 |
| STIMATE | STIM activating enhancer | 3.1665 |
| UBQLN2 | ubiquilin 2 | 3.09935 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 3.07006 |
| H2BC21 | H2B clustered histone 21 | 3.0511 |
| TBPL1 | TBP-like 1 | 3.03383 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.96606 |
| RPL39L | ribosomal protein L39-like | 2.89591 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.89054 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.8846 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.78554 |
| LCN2 | lipocalin 2 | 2.75233 |
| LOC122526780 | uncharacterized LOC122526780 | 2.74838 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.60728 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.6035 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.56931 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | 2.55562 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.51854 |
| SMIM40 | small integral membrane protein 40 | 2.49967 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 2.43824 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 2.36798 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.36628 |
| MYLK | myosin light chain kinase | 2.35038 |
| ABHD4 | abhydrolase domain containing 4 | 2.33136 |
| RAB21 | RAB21, member RAS oncogene family | 2.32395 |
| H1-2 | H1.2 linker histone, cluster member | 2.29829 |
| H2AC6 | H2A clustered histone 6 | 2.29616 |
| MEIS2 | Meis homeobox 2 | 2.26662 |
| TESK1 | testis-specific kinase 1 | 2.23934 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 2.21549 |
| SATB1 | SATB homeobox 1 | 2.21127 |
| NOSIP | nitric oxide synthase interacting protein | 2.18017 |
| KDM3A | lysine (K)-specific demethylase 3A | 2.15371 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.14971 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E | 2.1128 |
| AXIN1 | axin 1 | 2.06868 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 2.02739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -7.13816 |
| LDHD | lactate dehydrogenase D | -6.74522 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -6.314 |
| CDK1 | cyclin-dependent kinase 1 | -4.93543 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -4.6677 |
| UBE3C | ubiquitin protein ligase E3C | -4.43266 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -4.41525 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.88608 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.83497 |
| SLC35F2 | solute carrier family 35, member F2 | -3.82686 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.7772 |
| CDC25B | cell division cycle 25B | -3.65755 |
| HAT1 | histone acetyltransferase 1 | -3.47802 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.35512 |
| HMGA2 | high mobility group AT-hook 2 | -3.34404 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.33562 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.3118 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.27376 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -3.26334 |
| PCNA | proliferating cell nuclear antigen | -3.25168 |
| ICAM3 | intercellular adhesion molecule 3 | -3.24573 |
| TLCD3A | TLC domain containing 3A | -3.20159 |
| HYOU1 | hypoxia up-regulated 1 | -2.94803 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.8799 |
| TBC1D10C | TBC1 domain family, member 10C | -2.87922 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.83583 |
| GALE | UDP-galactose-4-epimerase | -2.82578 |
| PGM1 | phosphoglucomutase 1 | -2.78356 |
| TLR4 | toll-like receptor 4 | -2.78249 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.74784 |
| AURKB | aurora kinase B | -2.74179 |
| TCTN1 | tectonic family member 1 | -2.71749 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.67864 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.53278 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.51431 |
| HADH | hydroxyacyl-CoA dehydrogenase | -2.47557 |
| SKIC2 | SKI2 subunit of superkiller complex | -2.28329 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -2.22461 |
| CCNA2 | cyclin A2 | -2.21756 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.19421 |
| NNT | nicotinamide nucleotide transhydrogenase | -2.18397 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.16576 |
| TNIP1 | TNFAIP3 interacting protein 1 | -2.1264 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -2.12 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -2.06453 |
| SNX11 | sorting nexin 11 | -2.0557 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -2.04463 |
| FHL2 | four and a half LIM domains 2 | -2.01176 |
