CRCGN014_HEPG2_24H:B19 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_24H:B19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.87312
|
|
MAP7
|
microtubule-associated protein 7
|
6.41688
|
|
NOTCH1
|
notch 1
|
5.26166
|
|
UBQLN2
|
ubiquilin 2
|
5.15974
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.82132
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.49909
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.0141
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.77085
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.69785
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.67954
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.42137
|
|
PIH1D1
|
PIH1 domain containing 1
|
3.14766
|
|
SFTPB
|
surfactant protein B
|
2.87117
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.77894
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.49566
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.35013
|
|
SATB1
|
SATB homeobox 1
|
2.34351
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.25861
|
|
MRPS30
|
mitochondrial ribosomal protein S30
|
2.22942
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.22467
|
|
SETD6
|
SET domain containing 6
|
2.15877
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.06597
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-5.36016
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.28201
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.9723
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.93449
|
|
DSG2
|
desmoglein 2
|
-4.37886
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.2845
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.05109
|
|
LDHD
|
lactate dehydrogenase D
|
-4.03882
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.73726
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.63882
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.41129
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.97598
|
|
TLR4
|
toll-like receptor 4
|
-2.66936
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.63974
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.43812
|
|
ANXA8L1
|
annexin A8-like 1
|
-2.4054
|
|
ZW10
|
zw10 kinetochore protein
|
-2.27694
|
|
MTA1
|
metastasis associated 1
|
-2.08273
|
|
USB1
|
U6 snRNA biogenesis 1
|
-2.0659
|
|
SNIP1
|
Smad nuclear interacting protein 1
|
-2.02479
|