CRCGN014_HEPG2_24H:B20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethinyl estradiol 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN014_HEPG2_24H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 3.60092
MAP7 microtubule-associated protein 7 3.56061
ZNF589 zinc finger protein 589 3.44908
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.32145
STIMATE STIM activating enhancer 3.30691
ANO1 anoctamin 1, calcium activated chloride channel 2.63068
NOTCH1 notch 1 2.54926
PFKL phosphofructokinase, liver 2.53657
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.45426
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.21237
ABHD4 abhydrolase domain containing 4 2.15692
TRAM2 translocation associated membrane protein 2 2.1343
ABHD6 abhydrolase domain containing 6 2.11708
GATD3 glutamine amidotransferase class 1 domain containing 3 2.07542
GARRE1 granule associated Rac and RHOG effector 1 2.04208

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -9.36443
TSPAN4 tetraspanin 4 -4.52159
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.38737
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.87767
NT5DC2 5'-nucleotidase domain containing 2 -3.24422
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.4161