CRCGN014_HEPG2_24H:B21 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.19431
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.41544
|
|
MYLK
|
myosin light chain kinase
|
3.93141
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.87156
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.86656
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.76828
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.69175
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.56446
|
|
AXIN1
|
axin 1
|
3.55501
|
|
EPHB2
|
EPH receptor B2
|
3.3224
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
3.09623
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.07518
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.97801
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.95469
|
|
PRKCH
|
protein kinase C, eta
|
2.89931
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.81977
|
|
SPTLC2
|
serine palmitoyltransferase, long chain base subunit 2
|
2.56155
|
|
CYB561
|
cytochrome b561
|
2.26654
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.2375
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.23334
|
|
SFTPB
|
surfactant protein B
|
2.15368
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.1269
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.1248
|
|
CYP2A13
|
cytochrome P450, family 2, subfamily A, polypeptide 13
|
2.03395
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.68137
|
|
VAT1
|
vesicle amine transport 1
|
-4.42095
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.19953
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.19246
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.9583
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.92504
|
|
TSPAN4
|
tetraspanin 4
|
-3.63911
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.45234
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.41267
|
|
ZW10
|
zw10 kinetochore protein
|
-3.37159
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.92304
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.48855
|
|
CDC25B
|
cell division cycle 25B
|
-2.29369
|
|
PTPRG
|
protein tyrosine phosphatase, receptor type, G
|
-2.28228
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.14756
|
|
STX4
|
syntaxin 4
|
-2.10818
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.08233
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.01463
|
