CRCGN014_HEPG2_24H:B23 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SFTPB
|
surfactant protein B
|
4.10383
|
|
JADE2
|
jade family PHD finger 2
|
3.89308
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.8334
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.78923
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.58933
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.52564
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.26437
|
|
PIH1D1
|
PIH1 domain containing 1
|
3.17007
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.01114
|
|
MYLK
|
myosin light chain kinase
|
2.99007
|
|
MICALL1
|
MICAL-like 1
|
2.92988
|
|
PRR15L
|
proline rich 15-like
|
2.92365
|
|
INTS3
|
integrator complex subunit 3
|
2.80374
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.76644
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.75142
|
|
CDC45
|
cell division cycle 45
|
2.60426
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.45072
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.42291
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.3301
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.2594
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.11265
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.43435
|
|
CCNB2
|
cyclin B2
|
-4.8193
|
|
ZNF586
|
zinc finger protein 586
|
-4.41906
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.14725
|
|
LDHD
|
lactate dehydrogenase D
|
-3.80002
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.61304
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.60435
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.34566
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.30725
|
|
CDC20
|
cell division cycle 20
|
-3.30611
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.24777
|
|
RPS5
|
ribosomal protein S5
|
-3.19407
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.11596
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.99705
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.81193
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.71466
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.56006
|
|
VAT1
|
vesicle amine transport 1
|
-2.5362
|
|
TLR4
|
toll-like receptor 4
|
-2.12456
|
