CRCGN014_HEPG2_24H:B24 Gene Set
Genes
29 genes differentially expressed following the CRCGN014_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.1681
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.8741
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.58463
|
|
NOTCH1
|
notch 1
|
3.50186
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.39895
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.28223
|
|
NUP133
|
nucleoporin 133kDa
|
3.14773
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.01477
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.89481
|
|
PRKCH
|
protein kinase C, eta
|
2.61737
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.56057
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.24503
|
|
MAP7
|
microtubule-associated protein 7
|
2.19366
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.30918
|
|
TLR4
|
toll-like receptor 4
|
-4.51232
|
|
ZNF586
|
zinc finger protein 586
|
-4.37512
|
|
DSG2
|
desmoglein 2
|
-4.00202
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.90141
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.69667
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.66381
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.54478
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-3.4845
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.42036
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.39089
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.26766
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.82703
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.23387
|
|
DCK
|
deoxycytidine kinase
|
-2.21525
|
|
GNAS
|
GNAS complex locus
|
-2.17983
|
