CRCGN014_HEPG2_24H:C02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethoxane 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the CRCGN014_HEPG2_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPP38 ribonuclease P/MRP 38kDa subunit 5.71813
ADRB2 adrenoceptor beta 2, surface 5.34888
PPARG peroxisome proliferator-activated receptor gamma 5.33658
MAP7 microtubule-associated protein 7 4.44577
SNAP25 synaptosomal-associated protein, 25kDa 4.36238
SQOR sulfide quinone oxidoreductase 3.68005
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.64053
CXCL2 chemokine (C-X-C motif) ligand 2 3.28222
FZD7 frizzled class receptor 7 3.21799
HOOK2 hook microtubule-tethering protein 2 2.86547
CDPF1 cysteine-rich, DPF motif domain containing 1 2.51834
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.39068
PIH1D1 PIH1 domain containing 1 2.3583
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.35802
NUP133 nucleoporin 133kDa 2.35139
INTS3 integrator complex subunit 3 2.31257
BIRC2 baculoviral IAP repeat containing 2 2.20084
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.15743
GDI2 GDP dissociation inhibitor 2 2.09059
LOC122526780 uncharacterized LOC122526780 2.08141
FPGS folylpolyglutamate synthase 2.08033
COMMD10 COMM domain containing 10 2.05445

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -9.59695
NT5DC2 5'-nucleotidase domain containing 2 -5.65119
ADI1 acireductone dioxygenase 1 -4.99454
CD320 CD320 molecule -4.06049
CDC20 cell division cycle 20 -3.9971
ZMIZ1 zinc finger, MIZ-type containing 1 -3.46378
CCNB2 cyclin B2 -3.0928
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.94406
CSNK1E casein kinase 1, epsilon -2.5694
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.4952
MRPS2 mitochondrial ribosomal protein S2 -2.36722
EGF epidermal growth factor -2.32945
TEX10 testis expressed 10 -2.10481
TLR4 toll-like receptor 4 -2.02405
ZW10 zw10 kinetochore protein -2.01361