CRCGN014_HEPG2_24H:C05 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_24H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CBR3
|
carbonyl reductase 3
|
7.21118
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.9797
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.91972
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.77363
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.66168
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.40036
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.36499
|
|
CCNA1
|
cyclin A1
|
3.03324
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.96727
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.90445
|
|
KIF20A
|
kinesin family member 20A
|
2.67385
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.6417
|
|
KIF5C
|
kinesin family member 5C
|
2.62037
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.61218
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.59874
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.54388
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.50518
|
|
CRTAP
|
cartilage associated protein
|
2.39533
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.38175
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.34802
|
|
ZNF589
|
zinc finger protein 589
|
2.29507
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.29479
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.24442
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.16722
|
|
NUP133
|
nucleoporin 133kDa
|
2.00813
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.54988
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.95654
|
|
CDC20
|
cell division cycle 20
|
-3.70342
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.7028
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.61577
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.43362
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.28106
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.27219
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.80087
|
|
GDF15
|
growth differentiation factor 15
|
-2.7136
|
|
PLK1
|
polo-like kinase 1
|
-2.70901
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.69359
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.61194
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.51916
|
|
HTRA1
|
HtrA serine peptidase 1
|
-2.24865
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.17391
|
