CRCGN014_HEPG2_24H:C07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-ethyl-2-hexenal 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

40 genes differentially expressed following the CRCGN014_HEPG2_24H:C07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 6.85425
GPER1 G protein-coupled estrogen receptor 1 5.31969
STIMATE STIM activating enhancer 5.29881
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.6456
RPP38 ribonuclease P/MRP 38kDa subunit 3.46598
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.44227
CHMP6 charged multivesicular body protein 6 3.3124
C2CD2 C2 calcium-dependent domain containing 2 3.17229
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.07693
CIAO3 cytosolic iron-sulfur assembly component 3 2.8737
NMU neuromedin U 2.6766
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.5462
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.48604
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.45065
ABHD6 abhydrolase domain containing 6 2.36969
GPATCH8 G patch domain containing 8 2.16014
RXYLT1 ribitol xylosyltransferase 1 2.15618

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -4.85829
TLR4 toll-like receptor 4 -4.60013
MRPS2 mitochondrial ribosomal protein S2 -4.35491
UGDH UDP-glucose 6-dehydrogenase -4.14246
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.09914
ENOPH1 enolase-phosphatase 1 -3.90025
PLK1 polo-like kinase 1 -3.76225
ZDHHC6 zinc finger, DHHC-type containing 6 -3.61428
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.02991
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.0206
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.9481
TRAPPC3 trafficking protein particle complex 3 -2.9207
TSPAN4 tetraspanin 4 -2.78107
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.77519
OXA1L oxidase (cytochrome c) assembly 1-like -2.77081
CCNB1 cyclin B1 -2.76571
YME1L1 YME1-like 1 ATPase -2.57781
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.56804
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.45575
SNX11 sorting nexin 11 -2.38763
RGS2 regulator of G-protein signaling 2 -2.25312
CD320 CD320 molecule -2.18984
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.15746