CRCGN014_HEPG2_24H:C11 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_24H:C11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.82181
|
|
STK10
|
serine/threonine kinase 10
|
5.58672
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.61658
|
|
RPL39L
|
ribosomal protein L39-like
|
4.08852
|
|
LCN2
|
lipocalin 2
|
3.82615
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.36697
|
|
MYLK
|
myosin light chain kinase
|
3.35075
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.10927
|
|
GATA3
|
GATA binding protein 3
|
2.76717
|
|
HMOX1
|
heme oxygenase 1
|
2.72526
|
|
UBQLN2
|
ubiquilin 2
|
2.69572
|
|
CSK
|
c-src tyrosine kinase
|
2.64944
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.61423
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.55218
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.53999
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.51323
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.47228
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.35486
|
|
PFKL
|
phosphofructokinase, liver
|
2.34526
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.34513
|
|
PRKCH
|
protein kinase C, eta
|
2.25787
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.18662
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.18062
|
|
PRR15L
|
proline rich 15-like
|
2.18045
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.13409
|
|
SATB1
|
SATB homeobox 1
|
2.08576
|
|
BLCAP
|
bladder cancer associated protein
|
2.0591
|
|
AAMP
|
angio-associated, migratory cell protein
|
2.02724
|
|
ZNF589
|
zinc finger protein 589
|
2.00816
|
|
MOK
|
MOK protein kinase
|
2.00358
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-6.87974
|
|
ZNF586
|
zinc finger protein 586
|
-6.34031
|
|
C5
|
complement component 5
|
-3.56973
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.36376
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.2397
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.17327
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-3.08026
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.88457
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.81548
|
|
LDHD
|
lactate dehydrogenase D
|
-2.81132
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.56583
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.50143
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.48789
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.42288
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.4069
|
|
SNX11
|
sorting nexin 11
|
-2.32187
|
|
CEMIP
|
cell migration inducing protein, hyaluronan binding
|
-2.29744
|
|
TLR4
|
toll-like receptor 4
|
-2.08107
|
|
RBMX2
|
RNA binding motif protein, X-linked 2
|
-2.04588
|
