CRCGN014_HEPG2_24H:C14 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.96424
|
|
PLS1
|
plastin 1
|
5.17689
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.1187
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.73912
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.3688
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.26854
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.2205
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.05486
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.05254
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.9896
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.88847
|
|
KLHL21
|
kelch-like family member 21
|
2.68594
|
|
CHN1
|
chimerin 1
|
2.4658
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.43007
|
|
GATA3
|
GATA binding protein 3
|
2.2051
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.17907
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.16105
|
|
GATM
|
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
|
2.15636
|
|
PRR15L
|
proline rich 15-like
|
2.08767
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.60765
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.76253
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.87398
|
|
LDHD
|
lactate dehydrogenase D
|
-4.6874
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-3.56365
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.39928
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.38192
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.26553
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.24656
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.18787
|
|
DSG2
|
desmoglein 2
|
-3.13195
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.12579
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.11974
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.06598
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.9557
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-2.87467
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.75869
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.6362
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.6233
|
|
NVL
|
nuclear VCP-like
|
-2.59666
|
|
ZNF586
|
zinc finger protein 586
|
-2.58754
|
|
MICAL3
|
microtubule associated monooxygenase, calponin and LIM domain containing 3
|
-2.51308
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.37156
|
|
SNX11
|
sorting nexin 11
|
-2.13384
|
|
CTSD
|
cathepsin D
|
-2.13037
|
|
KLK5
|
kallikrein-related peptidase 5
|
-2.10068
|
|
REEP5
|
receptor accessory protein 5
|
-2.06673
|
|
TEX10
|
testis expressed 10
|
-2.03458
|
|
ALOX15B
|
arachidonate 15-lipoxygenase, type B
|
-2.00384
|
