CRCGN014_HEPG2_24H:C15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description citral 40.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN014_HEPG2_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.50359
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.73537
NOTCH1 notch 1 3.45746
ADGRE5 adhesion G protein-coupled receptor E5 3.13511
SFTPB surfactant protein B 3.07407
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.04879
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.04201
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.4534
BIRC2 baculoviral IAP repeat containing 2 2.26383
MAP7 microtubule-associated protein 7 2.25253
CHN1 chimerin 1 2.24358
STIMATE STIM activating enhancer 2.04004

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -5.38778
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.69338
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.42639
THAP11 THAP domain containing 11 -4.2804
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.06323
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.92431
NRIP1 nuclear receptor interacting protein 1 -2.83753
ZMIZ1 zinc finger, MIZ-type containing 1 -2.59067
TSPAN4 tetraspanin 4 -2.44701